| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Nuclear receptor subfamily 4 group A member 2 |
|---|
| Ligand | BDBM50250885 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_2227573 (CHEMBL5141086) |
|---|
| IC50 | 48000±n/a nM |
|---|
| Citation |  Willems, S; Merk, D Medicinal Chemistry and Chemical Biology of Nurr1 Modulators: An Emerging Strategy in Neurodegeneration. J Med Chem65:9548-9563 (2022) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Nuclear receptor subfamily 4 group A member 2 |
|---|
| Name: | Nuclear receptor subfamily 4 group A member 2 |
|---|
| Synonyms: | NOT | NR4A2 | NR4A2_HUMAN | NURR1 | TINUR |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 66603.77 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_453027 |
|---|
| Residue: | 598 |
|---|
| Sequence: | MPCVQAQYGSSPQGASPASQSYSYHSSGEYSSDFLTPEFVKFSMDLTNTEITATTSLPSF
STFMDNYSTGYDVKPPCLYQMPLSGQQSSIKVEDIQMHNYQQHSHLPPQSEEMMPHSGSV
YYKPSSPPTPTTPGFQVQHSPMWDDPGSLHNFHQNYVATTHMIEQRKTPVSRLSLFSFKQ
SPPGTPVSSCQMRFDGPLHVPMNPEPAGSHHVVDGQTFAVPNPIRKPASMGFPGLQIGHA
SQLLDTQVPSPPSRGSPSNEGLCAVCGDNAACQHYGVRTCEGCKGFFKRTVQKNAKYVCL
ANKNCPVDKRRRNRCQYCRFQKCLAVGMVKEVVRTDSLKGRRGRLPSKPKSPQEPSPPSP
PVSLISALVRAHVDSNPAMTSLDYSRFQANPDYQMSGDDTQHIQQFYDLLTGSMEIIRGW
AEKIPGFADLPKADQDLLFESAFLELFVLRLAYRSNPVEGKLIFCNGVVLHRLQCVRGFG
EWIDSIVEFSSNLQNMNIDISAFSCIAALAMVTERHGLKEPKRVEELQNKIVNCLKDHVT
FNNGGLNRPNYLSKLLGKLPELRTLCTQGLQRIFYLKLEDLVPPPAIIDKLFLDTLPF
|
|
|
|---|
| BDBM50250885 |
|---|
| n/a |
|---|
| Name | BDBM50250885 |
|---|
| Synonyms: | CHEBI:65019 | CHEMBL2270066 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C10H9NO2 |
|---|
| Mol. Mass. | 175.184 |
|---|
| SMILES | COC(=O)c1c[nH]c2ccccc12 |
|---|
| Structure | 
|
|---|
Search and Browse
