| Reaction Details |
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 | Report a problem with these data |
| Target | Integrase |
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| Ligand | BDBM50177217 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_332849 (CHEMBL859228) |
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| IC50 | >333000±n/a nM |
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| Citation |  Majerz-Maniecka, K; Musiol, R; Nitek, W; Oleksyn, BJ; Mouscadet, JF; Le Bret, M; Polanski, J Intermolecular interactions in the crystal structures of potential HIV-1 integrase inhibitors. Bioorg Med Chem Lett16:1005-9 (2006) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Integrase |
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| Name: | Integrase |
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| Synonyms: | Human immunodeficiency virus type 1 integrase |
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| Type: | PROTEIN |
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| Mol. Mass.: | 32231.48 |
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| Organism: | Human immunodeficiency virus 1 |
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| Description: | ChEMBL_90865 |
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| Residue: | 288 |
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| Sequence: | FLDGIDKAQDEHEKYHSNWRAMASDFNLPPVVAKEIVASCDKCQLKGEAMHGQVDCSPGI
WQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFLLKLAGRWPVKTIHTDNGSN
FTSTTVKAACWWAGIKQEFGIPYNPQSQGVVESMNKELKKIIGQVRDQAEHLKTAVQMAV
FIHNFKRKGGIGGYSAGERIVDIIATDIQTKELQKQITKIQNFRVYYRDSRDPLWKGPAK
LLWKGEGAVVIQDNSDIKVVPRRKVKIIRDYGKQMAGDDCVASRQDED
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| BDBM50177217 |
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| n/a |
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| Name | BDBM50177217 |
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| Synonyms: | 2-methyl-5-nitrosoquinolin-8-ol | CHEMBL202318 |
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| Type | Small organic molecule |
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| Emp. Form. | C10H8N2O2 |
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| Mol. Mass. | 188.1827 |
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| SMILES | Cc1ccc2c(ccc(O)c2n1)N=O |
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| Structure | 
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