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TargetSuccinate-semialdehyde dehydrogenase, mitochondrial
LigandBDBM50177405
Substrate/Competitorn/a
Meas. Tech.ChEMBL_332432 (CHEMBL867028)
IC50 15600±n/a nM
Citation Tao, YH; Yuan, Z; Tang, XQ; Xu, HB; Yang, XL Inhibition of GABA shunt enzymes' activity by 4-hydroxybenzaldehyde derivatives. Bioorg Med Chem Lett16:592-5 (2005) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Succinate-semialdehyde dehydrogenase, mitochondrial
Name:Succinate-semialdehyde dehydrogenase, mitochondrial
Synonyms:ALDH5A1 | Aldehyde dehydrogenase family 5 member A1 | NAD(+)-dependent succinic semialdehyde dehydrogenase | SSADH | SSDH_HUMAN | Succinate semialdehyde dehydrogenase | Succinate-semialdehyde dehydrogenase, mitochondrial
Type:PROTEIN
Mol. Mass.:57224.70
Organism:Homo sapiens (Human)
Description:ChEMBL_1459249
Residue:535
Sequence:
MATCIWLRSCGARRLGSTFPGCRLRPRAGGLVPASGPAPGPAQLRCYAGRLAGLSAALLR
TDSFVGGRWLPAAATFPVQDPASGAALGMVADCGVREARAAVRAAYEAFCRWREVSAKER
SSLLRKWYNLMIQNKDDLARIITAESGKPLKEAHGEILYSAFFLEWFSEEARRVYGDIIH
TPAKDRRALVLKQPIGVAAVITPWNFPSAMITRKVGAALAAGCTVVVKPAEDTPFSALAL
AELASQAGIPSGVYNVIPCSRKNAKEVGEAICTDPLVSKISFTGSTTTGKILLHHAANSV
KRVSMELGGLAPFIVFDSANVDQAVAGAMASKFRNTGQTCVCSNQFLVQRGIHDAFVKAF
AEAMKKNLRVGNGFEEGTTQGPLINEKAVEKVEKQVNDAVSKGATVVTGGKRHQLGKNFF
EPTLLCNVTQDMLCTHEETFGPLAPVIKFDTEEEAIAIANAADVGLAGYFYSQDPAQIWR
VAEQLEVGMVGVNEGLISSVECPFGGVKQSGLGREGSKYGIDEYLELKYVCYGGL
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  Blast E-value cutoff:
BDBM50177405
n/a
NameBDBM50177405
Synonyms:3-methoxy-4-hydroxybenzaldehyde | 4-hydroxy-3-methoxybenzaldehyde | 4-hydroxy-m-anisaldehyde | CHEMBL13883 | p-hydroxy-m-methoxybenzaldehyde | p-vanillin | vanillin
TypeSmall organic molecule
Emp. Form.C8H8O3
Mol. Mass.152.1473
SMILESCOc1cc(C=O)ccc1O
Structure
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