| Reaction Details |
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 | Report a problem with these data |
| Target | Succinate-semialdehyde dehydrogenase, mitochondrial |
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| Ligand | BDBM50177407 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_332432 (CHEMBL867028) |
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| IC50 | 350±n/a nM |
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| Citation |  Tao, YH; Yuan, Z; Tang, XQ; Xu, HB; Yang, XL Inhibition of GABA shunt enzymes' activity by 4-hydroxybenzaldehyde derivatives. Bioorg Med Chem Lett16:592-5 (2005) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Succinate-semialdehyde dehydrogenase, mitochondrial |
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| Name: | Succinate-semialdehyde dehydrogenase, mitochondrial |
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| Synonyms: | ALDH5A1 | Aldehyde dehydrogenase family 5 member A1 | NAD(+)-dependent succinic semialdehyde dehydrogenase | SSADH | SSDH_HUMAN | Succinate semialdehyde dehydrogenase | Succinate-semialdehyde dehydrogenase, mitochondrial |
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| Type: | PROTEIN |
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| Mol. Mass.: | 57224.70 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1459249 |
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| Residue: | 535 |
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| Sequence: | MATCIWLRSCGARRLGSTFPGCRLRPRAGGLVPASGPAPGPAQLRCYAGRLAGLSAALLR
TDSFVGGRWLPAAATFPVQDPASGAALGMVADCGVREARAAVRAAYEAFCRWREVSAKER
SSLLRKWYNLMIQNKDDLARIITAESGKPLKEAHGEILYSAFFLEWFSEEARRVYGDIIH
TPAKDRRALVLKQPIGVAAVITPWNFPSAMITRKVGAALAAGCTVVVKPAEDTPFSALAL
AELASQAGIPSGVYNVIPCSRKNAKEVGEAICTDPLVSKISFTGSTTTGKILLHHAANSV
KRVSMELGGLAPFIVFDSANVDQAVAGAMASKFRNTGQTCVCSNQFLVQRGIHDAFVKAF
AEAMKKNLRVGNGFEEGTTQGPLINEKAVEKVEKQVNDAVSKGATVVTGGKRHQLGKNFF
EPTLLCNVTQDMLCTHEETFGPLAPVIKFDTEEEAIAIANAADVGLAGYFYSQDPAQIWR
VAEQLEVGMVGVNEGLISSVECPFGGVKQSGLGREGSKYGIDEYLELKYVCYGGL
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| BDBM50177407 |
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| n/a |
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| Name | BDBM50177407 |
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| Synonyms: | 1-(4-hydroxyphenyl)prop-2-en-1-one | 4-acryloylphenol | CHEMBL378577 |
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| Type | Small organic molecule |
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| Emp. Form. | C9H8O2 |
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| Mol. Mass. | 148.1586 |
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| SMILES | Oc1ccc(cc1)C(=O)C=C |
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| Structure | 
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