| Reaction Details |
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 | Report a problem with these data |
| Target | 4-aminobutyrate aminotransferase, mitochondrial |
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| Ligand | BDBM50139370 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_332431 (CHEMBL867027) |
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| IC50 | >1000000±n/a nM |
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| Citation |  Tao, YH; Yuan, Z; Tang, XQ; Xu, HB; Yang, XL Inhibition of GABA shunt enzymes' activity by 4-hydroxybenzaldehyde derivatives. Bioorg Med Chem Lett16:592-5 (2005) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| 4-aminobutyrate aminotransferase, mitochondrial |
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| Name: | 4-aminobutyrate aminotransferase, mitochondrial |
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| Synonyms: | (S)-3-amino-2-methylpropionate transaminase | 4-aminobutyrate aminotransferase, mitochondrial | ABAT | GABA aminotransferase | GABA transaminase | GABA-AT | GABA-T | GABAT | GABT_HUMAN | Gamma-amino-N-butyrate transaminase | L-AIBAT |
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| Type: | PROTEIN |
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| Mol. Mass.: | 56449.39 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1459248 |
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| Residue: | 500 |
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| Sequence: | MASMLLAQRLACSFQHSYRLLVPGSRHISQAAAKVDVEFDYDGPLMKTEVPGPRSQELMK
QLNIIQNAEAVHFFCNYEESRGNYLVDVDGNRMLDLYSQISSVPIGYSHPALLKLIQQPQ
NASMFVNRPALGILPPENFVEKLRQSLLSVAPKGMSQLITMACGSCSNENALKTIFMWYR
SKERGQRGFSQEELETCMINQAPGCPDYSILSFMGAFHGRTMGCLATTHSKAIHKIDIPS
FDWPIAPFPRLKYPLEEFVKENQQEEARCLEEVEDLIVKYRKKKKTVAGIIVEPIQSEGG
DNHASDDFFRKLRDIARKHGCAFLVDEVQTGGGCTGKFWAHEHWGLDDPADVMTFSKKMM
TGGFFHKEEFRPNAPYRIFNTWLGDPSKNLLLAEVINIIKREDLLNNAAHAGKALLTGLL
DLQARYPQFISRVRGRGTFCSFDTPDDSIRNKLILIARNKGVVLGGCGDKSIRFRPTLVF
RDHHAHLFLNIFSDILADFK
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| BDBM50139370 |
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| n/a |
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| Name | BDBM50139370 |
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| Synonyms: | 4-Methoxy-benzaldehyde | 4-methoxybenzaldehyde | CHEMBL161598 |
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| Type | Small organic molecule |
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| Emp. Form. | C8H8O2 |
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| Mol. Mass. | 136.1479 |
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| SMILES | COc1ccc(C=O)cc1 |
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| Structure | 
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