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TargetSuccinate-semialdehyde dehydrogenase, mitochondrial
LigandBDBM50145829
Substrate/Competitorn/a
Meas. Tech.ChEMBL_332432 (CHEMBL867028)
IC50>1000000±n/a nM
Citation Tao, YH; Yuan, Z; Tang, XQ; Xu, HB; Yang, XL Inhibition of GABA shunt enzymes' activity by 4-hydroxybenzaldehyde derivatives. Bioorg Med Chem Lett16:592-5 (2005) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Succinate-semialdehyde dehydrogenase, mitochondrial
Name:Succinate-semialdehyde dehydrogenase, mitochondrial
Synonyms:ALDH5A1 | Aldehyde dehydrogenase family 5 member A1 | NAD(+)-dependent succinic semialdehyde dehydrogenase | SSADH | SSDH_HUMAN | Succinate semialdehyde dehydrogenase | Succinate-semialdehyde dehydrogenase, mitochondrial
Type:PROTEIN
Mol. Mass.:57224.70
Organism:Homo sapiens (Human)
Description:ChEMBL_1459249
Residue:535
Sequence:
MATCIWLRSCGARRLGSTFPGCRLRPRAGGLVPASGPAPGPAQLRCYAGRLAGLSAALLR
TDSFVGGRWLPAAATFPVQDPASGAALGMVADCGVREARAAVRAAYEAFCRWREVSAKER
SSLLRKWYNLMIQNKDDLARIITAESGKPLKEAHGEILYSAFFLEWFSEEARRVYGDIIH
TPAKDRRALVLKQPIGVAAVITPWNFPSAMITRKVGAALAAGCTVVVKPAEDTPFSALAL
AELASQAGIPSGVYNVIPCSRKNAKEVGEAICTDPLVSKISFTGSTTTGKILLHHAANSV
KRVSMELGGLAPFIVFDSANVDQAVAGAMASKFRNTGQTCVCSNQFLVQRGIHDAFVKAF
AEAMKKNLRVGNGFEEGTTQGPLINEKAVEKVEKQVNDAVSKGATVVTGGKRHQLGKNFF
EPTLLCNVTQDMLCTHEETFGPLAPVIKFDTEEEAIAIANAADVGLAGYFYSQDPAQIWR
VAEQLEVGMVGVNEGLISSVECPFGGVKQSGLGREGSKYGIDEYLELKYVCYGGL
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  Blast E-value cutoff:
BDBM50145829
n/a
NameBDBM50145829
Synonyms:4-Aminobenzoesaeure | 4-aminobenzoic acid | CHEMBL542 | PABA | p-Aminobenzoesaeure | p-aminobenzoic acid | para-aminobenzoic acid
TypeSmall organic molecule
Emp. Form.C7H7NO2
Mol. Mass.137.136
SMILESNc1ccc(cc1)C(O)=O
Structure
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