| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine receptor A3 |
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| Ligand | BDBM50039951 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_325473 (CHEMBL860157) |
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| Ki | 2.1±n/a nM |
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| Citation |  Catarzi, D; Colotta, V; Varano, F; Lenzi, O; Filacchioni, G; Trincavelli, L; Martini, C; Montopoli, C; Moro, S 1,2,4-Triazolo[1,5-a]quinoxaline as a versatile tool for the design of selective human A3 adenosine receptor antagonists: synthesis, biological evaluation, and molecular modeling studies of 2-(hetero)aryl- and 2-carboxy-substituted derivatives. J Med Chem48:7932-45 (2005) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosine receptor A3 |
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| Name: | Adenosine receptor A3 |
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| Synonyms: | A3 adenosine receptor (hA3) | AA3R_HUMAN | ADORA3 | Adenosine A3 receptor (A3AR) |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 36197.32 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P0DMS8 |
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| Residue: | 318 |
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| Sequence: | MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIA
VGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKR
VTTHRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMDYMVYF
SFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAFYGREFKTAKSLFLVLFLFA
LSWLPLSIINCIIYFNGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLLILKAC
VVCHPSDSLDTSIEKNSE
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| BDBM50039951 |
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| n/a |
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| Name | BDBM50039951 |
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| Synonyms: | 2-(4-Methoxy-phenyl)-5H-[1,2,4]triazolo[1,5-a]quinoxalin-4-one | 2-(4-methoxyphenyl)-[1,2,4]triazolo[1,5-a]quinoxalin-4(5H)-one | CHEMBL99178 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H12N4O2 |
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| Mol. Mass. | 292.2921 |
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| SMILES | COc1ccc(cc1)-c1nc2n(n1)c1ccccc1[nH]c2=O |
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| Structure | 
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