| Reaction Details |
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 | Report a problem with these data |
| Target | P2Y purinoceptor 6 |
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| Ligand | BDBM50118239 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_325347 (CHEMBL858654) |
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| EC50 | 86±n/a nM |
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| Citation |  Costanzi, S; Joshi, BV; Maddileti, S; Mamedova, L; Gonzalez-Moa, MJ; Marquez, VE; Harden, TK; Jacobson, KA Human P2Y(6) receptor: molecular modeling leads to the rational design of a novel agonist based on a unique conformational preference. J Med Chem48:8108-11 (2005) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| P2Y purinoceptor 6 |
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| Name: | P2Y purinoceptor 6 |
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| Synonyms: | P2RY6 | P2RY6_HUMAN | P2Y purinoceptor 6 | P2Y6 | Pyrimidinergic receptor P2Y6 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 36452.29 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1511151 |
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| Residue: | 328 |
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| Sequence: | MEWDNGTGQALGLPPTTCVYRENFKQLLLPPVYSAVLAAGLPLNICVITQICTSRRALTR
TAVYTLNLALADLLYACSLPLLIYNYAQGDHWPFGDFACRLVRFLFYANLHGSILFLTCI
SFQRYLGICHPLAPWHKRGGRRAAWLVCVAVWLAVTTQCLPTAIFAATGIQRNRTVCYDL
SPPALATHYMPYGMALTVIGFLLPFAALLACYCLLACRLCRQDGPAEPVAQERRGKAARM
AVVVAAAFAISFLPFHITKTAYLAVRSTPGVPCTVLEAFAAAYKGTRPFASANSVLDPIL
FYFTQKKFRRRPHELLQKLTAKWQRQGR
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| BDBM50118239 |
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| n/a |
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| Name | BDBM50118239 |
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| Synonyms: | CHEMBL130266 | UDP | Uridine diphosphate | uridine 5'-(trihydrogen diphosphate) |
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| Type | Small organic molecule |
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| Emp. Form. | C9H14N2O12P2 |
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| Mol. Mass. | 404.1612 |
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| SMILES | O[C@@H]1[C@@H](COP(O)(=O)OP(O)(O)=O)O[C@H]([C@@H]1O)n1ccc(=O)[nH]c1=O |r| |
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| Structure | 
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