| Reaction Details |
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 | Report a problem with these data |
| Target | Pantetheinase |
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| Ligand | BDBM50600540 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2234480 (CHEMBL5148252) |
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| IC50 | 230±n/a nM |
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| Citation |  Yoneyama, H; Hosohata, K; Jin, D; Yoshida, I; Toyoda, M; Kitamura, I; Takai, S; Usami, Y Design, synthesis, and evaluation of new vanin-1 inhibitors based on RR6. Bioorg Med Chem65:0 (2022) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Pantetheinase |
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| Name: | Pantetheinase |
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| Synonyms: | Pantetheine hydrolase | Tiff66 | VNN1 | VNN1_HUMAN | Vanin-1 | Vascular non-inflammatory molecule 1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 57002.46 |
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| Organism: | Homo sapiens (Human) |
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| Description: | O95497 |
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| Residue: | 513 |
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| Sequence: | MTTQLPAYVAILLFYVSRASCQDTFTAAVYEHAAILPNATLTPVSREEALALMNRNLDIL
EGAITSAADQGAHIIVTPEDAIYGWNFNRDSLYPYLEDIPDPEVNWIPCNNRNRFGQTPV
QERLSCLAKNNSIYVVANIGDKKPCDTSDPQCPPDGRYQYNTDVVFDSQGKLVARYHKQN
LFMGENQFNVPKEPEIVTFNTTFGSFGIFTCFDILFHDPAVTLVKDFHVDTIVFPTAWMN
VLPHLSAVEFHSAWAMGMRVNFLASNIHYPSKKMTGSGIYAPNSSRAFHYDMKTEEGKLL
LSQLDSHPSHSAVVNWTSYASSIEALSSGNKEFKGTVFFDEFTFVKLTGVAGNYTVCQKD
LCCHLSYKMSENIPNEVYALGAFDGLHTVEGRYYLQICTLLKCKTTNLNTCGDSAETAST
RFEMFSLSGTFGTQYVFPEVLLSENQLAPGEFQVSTDGRLFSLKPTSGPVLTVTLFGRLY
EKDWASNASSGLTAQARIIMLIVIAPIVCSLSW
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| BDBM50600540 |
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| n/a |
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| Name | BDBM50600540 |
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| Synonyms: | CHEMBL5173400 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H22FNO4 |
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| Mol. Mass. | 311.3486 |
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| SMILES | CC(C)(CO)[C@@H](O)C(=O)NCCC(=O)Cc1ccccc1F |r| |
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| Structure | 
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