| Reaction Details |
|---|
 | Report a problem with these data |
| Target | P2Y purinoceptor 12 |
|---|
| Ligand | BDBM50601863 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_2238426 (CHEMBL5152322) |
|---|
| EC50 | 60±n/a nM |
|---|
| Citation |  Chen, Z; Haider, A; Chen, J; Xiao, Z; Gobbi, L; Honer, M; Grether, U; Arnold, SE; Josephson, L; Liang, SH The Repertoire of Small-Molecule PET Probes for Neuroinflammation Imaging: Challenges and Opportunities beyond TSPO. J Med Chem64:17656-17689 (2021) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| P2Y purinoceptor 12 |
|---|
| Name: | P2Y purinoceptor 12 |
|---|
| Synonyms: | ADP-glucose receptor | ADPG-R | HORK3 | P2RY12 | P2T(AC) | P2Y purinoceptor 12 | P2Y(AC) | P2Y(ADP) | P2Y(cyc) | P2Y12 | P2Y12 platelet ADP receptor | P2Y12_HUMAN | Purinergic receptor P2Y12 | SP1999 |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 39458.48 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | Q9H244 |
|---|
| Residue: | 342 |
|---|
| Sequence: | MQAVDNLTSAPGNTSLCTRDYKITQVLFPLLYTVLFFVGLITNGLAMRIFFQIRSKSNFI
IFLKNTVISDLLMILTFPFKILSDAKLGTGPLRTFVCQVTSVIFYFTMYISISFLGLITI
DRYQKTTRPFKTSNPKNLLGAKILSVVIWAFMFLLSLPNMILTNRQPRDKNVKKCSFLKS
EFGLVWHEIVNYICQVIFWINFLIVIVCYTLITKELYRSYVRTRGVGKVPRKKVNVKVFI
IIAVFFICFVPFHFARIPYTLSQTRDVFDCTAENTLFYVKESTLWLTSLNACLDPFIYFF
LCKSFRNSLISMLKCPNSATSLSQDNRKKEQDGGDPNEETPM
|
|
|
|---|
| BDBM50601863 |
|---|
| n/a |
|---|
| Name | BDBM50601863 |
|---|
| Synonyms: | CHEMBL5179763 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C19H21ClF3NO2 |
|---|
| Mol. Mass. | 386.824 |
|---|
| SMILES | [11CH3]Oc1ccc(Cl)c(c1)C(=O)NCC12CC3(F)CC(F)(CC(F)(C3)C1)C2 |TLB:17:18:24:23.15.14,16:15:20.18.25:24,19:18:24:23.15.14,12:13:20:23.17.15,THB:17:15:20.18.25:24,14:15:20:25.13.24,14:13:20:23.17.15,16:15:20:25.13.24| |
|---|
| Structure | 
|
|---|
Search and Browse
