| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Melanocortin receptor 4 |
|---|
| Ligand | BDBM50182081 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_348051 (CHEMBL868466) |
|---|
| Ki | 900±n/a nM |
|---|
| Citation |  Vos, TJ; Balani, S; Blackburn, C; Chau, RW; Danca, MD; Drabic, SV; Farrer, CA; Patane, MA; Stroud, SG; Yowe, DL; Claiborne, CF Identification and structure-activity relationships of a new series of Melanocortin-4 receptor antagonists. Bioorg Med Chem Lett16:2302-5 (2006) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Melanocortin receptor 4 |
|---|
| Name: | Melanocortin receptor 4 |
|---|
| Synonyms: | MC4-R | MC4R | MC4R_HUMAN | Melanocortin MC4 | Melanocortin receptor 4 (MC-4) | Melanocortin receptor 4 (MC4-R) | Melanocortin receptor 4 (MC4R) |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 36949.50 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P32245 |
|---|
| Residue: | 332 |
|---|
| Sequence: | MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLL
ENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVN
IDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVS
GILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGAN
MKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPL
IYALRSQELRKTFKEIICCYPLGGLCDLSSRY
|
|
|
|---|
| BDBM50182081 |
|---|
| n/a |
|---|
| Name | BDBM50182081 |
|---|
| Synonyms: | CHEMBL205461 | N-[2-(5-bromo-2-methoxy-benzyloxy)-3-fluoro-benzoyl]-N'-(4-diethylamino-1-methyl-butyl)-guanidine |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C25H34BrFN4O3 |
|---|
| Mol. Mass. | 537.465 |
|---|
| SMILES | CCN(CC)CCCC(C)N=C(N)NC(=O)c1cccc(F)c1OCc1cc(Br)ccc1OC |w:10.9| |
|---|
| Structure | 
|
|---|
Search and Browse
