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TargetP2X purinoceptor 7
LigandBDBM76863
Substrate/Competitorn/a
Meas. Tech.ChEMBL_2238739 (CHEMBL5152635)
IC50 830±n/a nM
Citation Yamagiwa, N; Komine, M; Hanaoka, F; Nobuta, T; Yoshida, K; Ito, M; Matsuoka, I Exploratory study of oxatomide derivatives with high P2X Bioorg Med Chem Lett77:0 (2022) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
P2X purinoceptor 7
Name:P2X purinoceptor 7
Synonyms:ATP receptor | P2RX7 | P2RX7_HUMAN | P2X purinoceptor 7 (P2RX7) | P2X purinoceptor 7 (P2X7) | P2X7 | P2Z receptor | Purinergic receptor
Type:Protein
Mol. Mass.:68602.85
Organism:Homo sapiens (Human)
Description:Q99572
Residue:595
Sequence:
MPACCSCSDVFQYETNKVTRIQSMNYGTIKWFFHVIIFSYVCFALVSDKLYQRKEPVISS
VHTKVKGIAEVKEEIVENGVKKLVHSVFDTADYTFPLQGNSFFVMTNFLKTEGQEQRLCP
EYPTRRTLCSSDRGCKKGWMDPQSKGIQTGRCVVYEGNQKTCEVSAWCPIEAVEEAPRPA
LLNSAENFTVLIKNNIDFPGHNYTTRNILPGLNITCTFHKTQNPQCPIFRLGDIFRETGD
NFSDVAIQGGIMGIEIYWDCNLDRWFHHCRPKYSFRRLDDKTTNVSLYPGYNFRYAKYYK
ENNVEKRTLIKVFGIRFDILVFGTGGKFDIIQLVVYIGSTLSYFGLAAVFIDFLIDTYSS
NCCRSHIYPWCKCCQPCVVNEYYYRKKCESIVEPKPTLKYVSFVDESHIRMVNQQLLGRS
LQDVKGQEVPRPAMDFTDLSRLPLALHDTPPIPGQPEEIQLLRKEATPRSRDSPVWCQCG
SCLPSQLPESHRCLEELCCRKKPGACITTSELFRKLVLSRHVLQFLLLYQEPLLALDVDS
TNSRLRHCAYRCYATWRFGSQDMADFAILPSCCRWRIRKEFPKSEGQYSGFKSPY
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM76863
n/a
NameBDBM76863
Synonyms:3-[3-(4-benzhydrylpiperazin-1-yl)propyl]-1H-benzimidazol-2-one | 3-[3-(4-benzhydrylpiperazino)propyl]-1H-benzimidazol-2-one | 3-[3-[4-(diphenylmethyl)-1-piperazinyl]propyl]-1H-benzimidazol-2-one | 3-[3-[4-(diphenylmethyl)piperazin-1-yl]propyl]-1H-benzimidazol-2-one | MLS000028549 | OXATOMIDE | SMR000058301 | cid_4615
TypeSmall organic molecule
Emp. Form.C27H30N4O
Mol. Mass.426.5533
SMILESO=c1[nH]c2ccccc2n1CCCN1CCN(CC1)C(c1ccccc1)c1ccccc1
Structure
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