| Reaction Details |
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 | Report a problem with these data |
| Target | Potassium voltage-gated channel subfamily A member 3 |
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| Ligand | BDBM50182593 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_334895 (CHEMBL861270) |
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| EC50 | 450±n/a nM |
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| Citation |  Harvey, AJ; Baell, JB; Toovey, N; Homerick, D; Wulff, H A new class of blockers of the voltage-gated potassium channel Kv1.3 via modification of the 4- or 7-position of khellinone. J Med Chem49:1433-41 (2006) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Potassium voltage-gated channel subfamily A member 3 |
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| Name: | Potassium voltage-gated channel subfamily A member 3 |
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| Synonyms: | KCNA3_MOUSE | Kcna3 | MK3 | Potassium voltage-gated channel subfamily A member 3 | Voltage-gated potassium channel subunit Kv1.3 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 58553.58 |
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| Organism: | Mus musculus |
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| Description: | ChEMBL_1513943 |
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| Residue: | 528 |
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| Sequence: | MTVVPGDHLLEPEAAGGGGGDPPQGGCGSGGGGGGCDRYEPLPPALPAAGEQDCCGERVV
INISGLRFETQLKTLCQFPETLLGDPKRRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGG
RIRRPVNVPIDIFSEEIRFYQLGEEAMEKFREDEGFLREEERPLPRRDFQRQVWLLFEYP
ESSGPARGIAIVSVLVILISIVIFCLETLPEFRDEKDYPASPSQDVFEAANNSTSGAPSG
ASSFSDPFFVVETLCIIWFSFELLVRFFACPSKATFSRNIMNLIDIVAIIPYFITLGTEL
AERQGNGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFI
GVILFSSAVYFAEADDPSSGFNSIPDAFWWAVVTMTTVGYGDMHPVTIGGKIVGSLCAIA
GVLTIALPVPVIVSNFNYFYHRETEGEEQAQYMHVGSCQHLSSSAEELRKARSNSTLSKS
EYMVIEEGGMNHSAFPQTPFKTGNSTATCTTNNNPNSCVNIKKIFTDV
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| BDBM50182593 |
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| n/a |
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| Name | BDBM50182593 |
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| Synonyms: | 1-(7-(3-(trifluoromethoxy)benzyloxy)-6-hydroxy-4-methoxybenzofuran-5-yl)ethanone | CHEMBL202572 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H15F3O6 |
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| Mol. Mass. | 396.314 |
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| SMILES | COc1c(C(C)=O)c(O)c(OCc2cccc(OC(F)(F)F)c2)c2occc12 |
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| Structure | 
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