| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Potassium voltage-gated channel subfamily A member 5 |
|---|
| Ligand | BDBM50182597 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_334900 (CHEMBL861278) |
|---|
| EC50 | 5000±n/a nM |
|---|
| Citation |  Harvey, AJ; Baell, JB; Toovey, N; Homerick, D; Wulff, H A new class of blockers of the voltage-gated potassium channel Kv1.3 via modification of the 4- or 7-position of khellinone. J Med Chem49:1433-41 (2006) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Potassium voltage-gated channel subfamily A member 5 |
|---|
| Name: | Potassium voltage-gated channel subfamily A member 5 |
|---|
| Synonyms: | HK2 | HPCN1 | KCNA5 | KCNA5_HUMAN | Potassium voltage-gated channel subfamily A member 5 | Voltage-gated potassium channel | Voltage-gated potassium channel subunit Kv1.5 |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 67222.47 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P22460 |
|---|
| Residue: | 613 |
|---|
| Sequence: | MEIALVPLENGGAMTVRGGDEARAGCGQATGGELQCPPTAGLSDGPKEPAPKGRGAQRDA
DSGVRPLPPLPDPGVRPLPPLPEELPRPRRPPPEDEEEEGDPGLGTVEDQALGTASLHHQ
RVHINISGLRFETQLGTLAQFPNTLLGDPAKRLRYFDPLRNEYFFDRNRPSFDGILYYYQ
SGGRLRRPVNVSLDVFADEIRFYQLGDEAMERFREDEGFIKEEEKPLPRNEFQRQVWLIF
EYPESSGSARAIAIVSVLVILISIITFCLETLPEFRDERELLRHPPAPHQPPAPAPGANG
SGVMAPPSGPTVAPLLPRTLADPFFIVETTCVIWFTFELLVRFFACPSKAGFSRNIMNII
DVVAIFPYFITLGTELAEQQPGGGGGGQNGQQAMSLAILRVIRLVRVFRIFKLSRHSKGL
QILGKTLQASMRELGLLIFFLFIGVILFSSAVYFAEADNQGTHFSSIPDAFWWAVVTMTT
VGYGDMRPITVGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETDHEEPAVLKEEQG
TQSQGPGLDRGVQRKVSGSRGSFCKAGGTLENADSARRGSCPLEKCNVKAKSNVDLRRSL
YALCLDTSRETDL
|
|
|
|---|
| BDBM50182597 |
|---|
| n/a |
|---|
| Name | BDBM50182597 |
|---|
| Synonyms: | 5-acetyl-4,7-benzyloxy-6-hydroxybenzofuran | CHEMBL203909 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C24H20O5 |
|---|
| Mol. Mass. | 388.4126 |
|---|
| SMILES | CC(=O)c1c(O)c(OCc2ccccc2)c2occc2c1OCc1ccccc1 |
|---|
| Structure | 
|
|---|
Search and Browse
