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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Reverse transcriptase/RNaseH | ||
| Ligand | BDBM50183202 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_355438 (CHEMBL868998) | ||
| IC50 | 55±n/a nM | ||
| Citation |  Muraglia, E; Kinzel, OD; Laufer, R; Miller, MD; Moyer, G; Munshi, V; Orvieto, F; Palumbi, MC; Pescatore, G; Rowley, M; Williams, PD; Summa, V Tetrazole thioacetanilides: potent non-nucleoside inhibitors of WT HIV reverse transcriptase and its K103N mutant. Bioorg Med Chem Lett16:2748-52 (2006) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Reverse transcriptase/RNaseH | |||
| Name: | Reverse transcriptase/RNaseH | ||
| Synonyms: | HIV-1 Reverse Transcriptase RNase H | Human immunodeficiency virus type 1 reverse transcriptase | Reverse transcriptase/RNaseH | ||
| Type: | PROTEIN | ||
| Mol. Mass.: | 65229.15 | ||
| Organism: | Human immunodeficiency virus 1 | ||
| Description: | ChEMBL_1473730 | ||
| Residue: | 566 | ||
| Sequence: |
| ||
| BDBM50183202 | |||
| n/a | |||
| Name | BDBM50183202 | ||
| Synonyms: | 4-(2-(1-mesityl-1H-tetrazol-5-ylthio)acetamido)-3-methylbenzamide | CHEMBL207746 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C20H22N6O2S | ||
| Mol. Mass. | 410.493 | ||
| SMILES | Cc1cc(C)c(c(C)c1)-n1nnnc1SCC(=O)Nc1ccc(cc1C)C(N)=O |(-6.75,-23.61,;-6.42,-22.1,;-7.56,-21.06,;-7.22,-19.56,;-8.36,-18.52,;-5.76,-19.09,;-4.62,-20.12,;-3.15,-19.65,;-4.95,-21.64,;-5.43,-17.58,;-6.46,-16.43,;-5.68,-15.1,;-4.18,-15.42,;-4.03,-16.96,;-2.69,-17.73,;-1.36,-16.96,;-.03,-17.73,;-.03,-19.27,;1.31,-16.97,;2.64,-17.74,;2.63,-19.28,;3.96,-20.05,;5.3,-19.28,;5.3,-17.74,;3.97,-16.97,;3.97,-15.43,;6.64,-20.05,;7.97,-19.28,;6.63,-21.59,)| | ||
| Structure | 
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