| Reaction Details |
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 | Report a problem with these data |
| Target | Alpha-1D adrenergic receptor |
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| Ligand | BDBM56339 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_350832 (CHEMBL869686) |
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| EC50 | 790±n/a nM |
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| Citation |  del Olmo, E; Barboza, B; Ybarra, MI; López-Pérez, JL; Carrón, R; Sevilla, MA; Boselli, C; San Feliciano, A Vasorelaxant activity of phthalazinones and related compounds. Bioorg Med Chem Lett16:2786-90 (2006) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Alpha-1D adrenergic receptor |
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| Name: | Alpha-1D adrenergic receptor |
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| Synonyms: | ADA1D_RAT | Adra1a | Adra1d | Alpha adrenergic receptor 1A and 1D | Alpha-1D adrenergic receptor | Serotonin 1a (5-HT1a) receptor/Adrenergic receptor alpha-1 |
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| Type: | Protein |
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| Mol. Mass.: | 59375.97 |
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| Organism: | Rattus norvegicus (Rat) |
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| Description: | P23944 |
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| Residue: | 561 |
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| Sequence: | MTFRDILSVTFEGPRSSSSTGGSGAGGGAGTVGPEGGAVGGVPGATGGGAVVGTGSGEDN
QSSTGEPGAAASGEVNGSAAVGGLVVSAQGVGVGVFLAAFILTAVAGNLLVILSVACNRH
LQTVTNYFIVNLAVADLLLSAAVLPFSATMEVLGFWAFGRTFCDVWAAVDVLCCTASILS
LCTISVDRYVGVRHSLKYPAIMTERKAAAILALLWAVALVVSVGPLLGWKEPVPPDERFC
GITEEVGYAIFSSVCSFYLPMAVIVVMYCRVYVVARSTTRSLEAGIKREPGKASEVVLRI
HCRGAATSAKGYPGTQSSKGHTLRSSLSVRLLKFSREKKAAKTLAIVVGVFVLCWFPFFF
VLPLGSLFPQLKPSEGVFKVIFWLGYFNSCVNPLIYPCSSREFKRAFLRLLRCQCRRRRR
RLWAVYGHHWRASTGDARSDCAPSPRIAPPGAPLALTAHPGAGSADTPETQDSVSSSRKP
ASALREWRLLGPLQRPTTQLRAKVSSLSHKIRSGARRAETACALRSEVEAVSLNVPQDGA
EAVICQAYEPGDYSNLRETDI
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| BDBM56339 |
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| n/a |
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| Name | BDBM56339 |
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| Synonyms: | 4-(4-chlorobenzyl)-1(2H)-phthalazinone | 4-(4-chlorobenzyl)-2H-phthalazin-1-one | 4-[(4-chlorophenyl)methyl]-2H-phthalazin-1-one | CHEMBL63976 | MLS000547504 | SMR000113649 | cid_104452 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H11ClN2O |
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| Mol. Mass. | 270.714 |
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| SMILES | Clc1ccc(Cc2n[nH]c(=O)c3ccccc23)cc1 |
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| Structure | 
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