| Reaction Details |
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 | Report a problem with these data |
| Target | Peroxisome proliferator-activated receptor delta |
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| Ligand | BDBM50184668 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_355606 (CHEMBL853178) |
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| EC50 | 110±n/a nM |
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| Citation |  Epple, R; Azimioara, M; Russo, R; Bursulaya, B; Tian, SS; Gerken, A; Iskandar, M 1,3,5-Trisubstituted aryls as highly selective PPARdelta agonists. Bioorg Med Chem Lett16:2969-73 (2006) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Peroxisome proliferator-activated receptor delta |
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| Name: | Peroxisome proliferator-activated receptor delta |
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| Synonyms: | NR1C2 | NUC1 | NUCI | Nuclear hormone receptor 1 | Nuclear receptor subfamily 1 group C member 2 | PPAR delta | PPAR-beta | PPARB | PPARD | PPARD_HUMAN | Peroxisome proliferator-activated receptor | Peroxisome proliferator-activated receptor beta | Peroxisome proliferator-activated receptor delta |
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| Type: | Enzyme |
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| Mol. Mass.: | 49910.45 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q03181 |
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| Residue: | 441 |
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| Sequence: | MEQPQEEAPEVREEEEKEEVAEAEGAPELNGGPQHALPSSSYTDLSRSSSPPSLLDQLQM
GCDGASCGSLNMECRVCGDKASGFHYGVHACEGCKGFFRRTIRMKLEYEKCERSCKIQKK
NRNKCQYCRFQKCLALGMSHNAIRFGRMPEAEKRKLVAGLTANEGSQYNPQVADLKAFSK
HIYNAYLKNFNMTKKKARSILTGKASHTAPFVIHDIETLWQAEKGLVWKQLVNGLPPYKE
ISVHVFYRCQCTTVETVRELTEFAKSIPSFSSLFLNDQVTLLKYGVHEAIFAMLASIVNK
DGLLVANGSGFVTREFLRSLRKPFSDIIEPKFEFAVKFNALELDDSDLALFIAAIILCGD
RPGLMNVPRVEAIQDTILRALEFHLQANHPDAQYLFPKLLQKMADLRQLVTEHAQMMQRI
KKTETETSLHPLLQEIYKDMY
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| BDBM50184668 |
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| n/a |
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| Name | BDBM50184668 |
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| Synonyms: | CHEMBL377695 | [4-(4,4''-dichloro-[1,1';3',1'']terphenyl-5'-ylmethoxy)-2-methyl-phenoxy]-acetic acid |
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| Type | Small organic molecule |
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| Emp. Form. | C28H22Cl2O4 |
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| Mol. Mass. | 493.378 |
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| SMILES | Cc1cc(OCc2cc(cc(c2)-c2ccc(Cl)cc2)-c2ccc(Cl)cc2)ccc1OCC(O)=O |
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| Structure | 
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