Ki Summary

Reaction Details

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Target

Neuropeptides B/W receptor type 1

Ligand

BDBM50603462

Substrate/Competitor

n/a

Meas. Tech.

ChEMBL_2244049 (CHEMBL5158259)

IC50

113±n/a nM

Citation

Nguyen, T; Decker, AM; Snyder, RW; Tonetti, EC; Gamage, TF; Zhang, Y Neuropeptide B/W receptor 1 peptidomimetic agonists: Structure-activity relationships and plasma stability. Eur J Med Chem231:0 (2022) [PubMed] Article

More Info.:

Get all data from this article, Assay Method

Neuropeptides B/W receptor type 1

Name:

Neuropeptides B/W receptor type 1

Synonyms:

GPR7 | NPBW1_HUMAN | NPBWR1 | neuropeptides B/W receptor 1

Type:

Enzyme Catalytic Domain

Mol. Mass.:

36111.82

Organism:

Homo sapiens (Human)

Description:

gi_119607128

Residue:

328

Sequence:

MDNASFSEPWPANASGPDPALSCSNASTLAPLPAPLAVAVPVVYAVICAVGLAGNSAVLY
VLLRAPRMKTVTNLFILNLAIADELFTLVLPINIADFLLRQWPFGELMCKLIVAIDQYNT
FSSLYFLTVMSADRYLVVLATAESRRVAGRTYSAARAVSLAVWGIVTLVVLPFAVFARLD
DEQGRRQCVLVFPQPEAFWWRASRLYTLVLGFAIPVSTICVLYTTLLCRLHAMRLDSHAK
ALERAKKRVTFLVVAILAVCLLCWTPYHLSTVVALTTDLPQTPLVIAISYFITSLSYANS
CLNPFLYAFLDASFRRNLRQLITCRAAA

BDBM50603462

n/a

Name

BDBM50603462

Synonyms:

CHEMBL5198182

Type

Small organic molecule

Emp. Form.

C85H141N19O15

Mol. Mass.

1669.1473

SMILES

CCCCCCCCCCCCCCCC(=O)NCCCC[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](N)Cc1c[nH]c2ccccc12)C(=O)NCCCCC(=O)NCCCCC(=O)NCCCCC(=O)NCC(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(N)=O |r|

Structure