| Reaction Details |
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 | Report a problem with these data |
| Target | G-protein coupled receptor 84 |
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| Ligand | BDBM50603890 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2245452 (CHEMBL5159662) |
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| IC50 | 165±n/a nM |
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| Citation |  Chen, LH; Zhang, Q; Xiao, YF; Fang, YC; Xie, X; Nan, FJ Phosphodiesters as GPR84 Antagonists for the Treatment of Ulcerative Colitis. J Med Chem65:3991-4006 (2022) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| G-protein coupled receptor 84 |
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| Name: | G-protein coupled receptor 84 |
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| Synonyms: | EX33 | G-protein coupled receptor 84 | GPR84 | GPR84_HUMAN | Inflammation-related G-protein coupled receptor EX33 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 43726.73 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_116040 |
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| Residue: | 396 |
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| Sequence: | MWNSSDANFSCYHESVLGYRYVAVSWGVVVAVTGTVGNVLTLLALAIQPKLRTRFNLLIA
NLTLADLLYCTLLQPFSVDTYLHLHWRTGATFCRVFGLLLFASNSVSILTLCLIALGRYL
LIAHPKLFPQVFSAKGIVLALVSTWVVGVASFAPLWPIYILVPVVCTCSFDRIRGRPYTT
ILMGIYFVLGLSSVGIFYCLIHRQVKRAAQALDQYKLRQASIHSNHVARTDEAMPGRFQE
LDSRLASGGPSEGISSEPVSAATTQTLEGDSSEVGDQINSKRAKQMAEKSPPEASAKAQP
IKGARRAPDSSSEFGKVTRMCFAVFLCFALSYIPFLLLNILDARVQAPRVVHMLAANLTW
LNGCINPVLYAAMNRQFRQAYGSILKRGPRSFHRLH
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| BDBM50603890 |
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| n/a |
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| Name | BDBM50603890 |
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| Synonyms: | CHEMBL5203023 |
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| Type | Small organic molecule |
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| Emp. Form. | C28H16F2NaO4PS2 |
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| Mol. Mass. | 572.515 |
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| SMILES | [Na;v0+].[#8-]P(=O)([#8]-[#6]-1=[#6]-c2ccccc2-[#16]-c2ccc(F)cc-12)[#8]-[#6]-1=[#6]-c2ccccc2-[#16]-c2ccc(F)cc-12 |t:4,24| |
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| Structure | 
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