| Reaction Details |
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 | Report a problem with these data |
| Target | Proteasome subunit beta type-4 |
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| Ligand | BDBM50604324 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2247518 (CHEMBL5161728) |
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| IC50 | >40000±n/a nM |
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| Citation |  Nan, G; Huang, L; Li, Y; Yang, Y; Yang, Y; Li, K; Lai, F; Chen, X; Xiao, Z Identification of N, C-capped di- and tripeptides as selective immunoproteasome inhibitors. Eur J Med Chem234:0 (2022) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Proteasome subunit beta type-4 |
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| Name: | Proteasome subunit beta type-4 |
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| Synonyms: | 26 kDa prosomal protein | HsBPROS26 | HsN3 | Macropain beta chain | Multicatalytic endopeptidase complex beta chain | PROS-26 | PROS26 | PSB4_HUMAN | PSMB4 | Proteasome beta chain | Proteasome chain 3 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 29202.40 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_106197 |
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| Residue: | 264 |
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| Sequence: | MEAFLGSRSGLWAGGPAPGQFYRIPSTPDSFMDPASALYRGPITRTQNPMVTGTSVLGVK
FEGGVVIAADMLGSYGSLARFRNISRIMRVNNSTMLGASGDYADFQYLKQVLGQMVIDEE
LLGDGHSYSPRAIHSWLTRAMYSRRSKMNPLWNTMVIGGYADGESFLGYVDMLGVAYEAP
SLATGYGAYLAQPLLREVLEKQPVLSQTEARDLVERCMRVLYYRDARSYNRFQIATVTEK
GVEIEGPLSTETNWDIAHMISGFE
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| BDBM50604324 |
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| n/a |
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| Name | BDBM50604324 |
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| Synonyms: | CHEMBL5183361 |
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| Type | Small organic molecule |
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| Emp. Form. | C37H44N6O6 |
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| Mol. Mass. | 668.7819 |
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| SMILES | Cc1ccc(CNC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCC(=O)NC(C)(C)C)NC(=O)CCNC(=O)C(=C\c2ccco2)\C#N)cc1 |r| |
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| Structure | 
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