| Reaction Details |
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 | Report a problem with these data |
| Target | Beta-mannosidase |
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| Ligand | BDBM50186736 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_353431 (CHEMBL865091) |
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| pH | 4±n/a |
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| Ki | >1000000±n/a nM |
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| Comments | extracted |
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| Citation |  Wang, RW; Qiu, XL; Bols, M; Ortega-Caballero, F; Qing, FL Synthesis and biological evaluation of glycosidase inhibitors: gem-difluoromethylenated nojirimycin analogues. J Med Chem49:2989-97 (2006) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Beta-mannosidase |
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| Name: | Beta-mannosidase |
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| Synonyms: | Lysosomal beta A mannosidase | MANB1 | MANBA | MANBA_HUMAN | Mannanase | Mannase |
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| Type: | PROTEIN |
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| Mol. Mass.: | 100878.33 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_41367 |
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| Residue: | 879 |
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| Sequence: | MRLHLLLLLALCGAGTTAAELSYSLRGNWSICNGNGSLELPGAVPGCVHSALFQQGLIQD
SYYRFNDLNYRWVSLDNWTYSKEFKIPFEISKWQKVNLILEGVDTVSKILFNEVTIGETD
NMFNRYSFDITNVVRDVNSIELRFQSAVLYAAQQSKAHTRYQVPPDCPPLVQKGECHVNF
VRKEQCSFSWDWGPSFPTQGIWKDVRIEAYNICHLNYFTFSPIYDKSAQEWNLEIESTFD
VVSSKPVGGQVIVAIPKLQTQQTYSIELQPGKRIVELFVNISKNITVETWWPHGHGNQTG
YNMTVLFELDGGLNIEKSAKVYFRTVELIEEPIKGSPGLSFYFKINGFPIFLKGSNWIPA
DSFQDRVTSELLRLLLQSVVDANMNTLRVWGGGIYEQDEFYELCDELGIMVWQDFMFACA
LYPTDQGFLDSVTAEVAYQIKRLKSHPSIIIWSGNNENEEALMMNWYHISFTDRPIYIKD
YVTLYVKNIRELVLAGDKSRPFITSSPTNGAETVAEAWVSQNPNSNYFGDVHFYDYISDC
WNWKVFPKARFASEYGYQSWPSFSTLEKVSSTEDWSFNSKFSLHRQHHEGGNKQMLYQAG
LHFKLPQSTDPLRTFKDTIYLTQVMQAQCVKTETEFYRRSRSEIVDQQGHTMGALYWQLN
DIWQAPSWASLEYGGKWKMLHYFAQNFFAPLLPVGFENENTFYIYGVSDLHSDYSMTLSV
RVHTWSSLEPVCSRVTERFVMKGGEAVCLYEEPVSELLRRCGNCTRESCVVSFYLSADHE
LLSPTNYHFLSSPKEAVGLCKAQITAIISQQGDIFVFDLETSAVAPFVWLDVGSIPGRFS
DNGFLMTEKTRTILFYPWEPTSKNELEQSFHVTSLTDIY
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| BDBM50186736 |
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| n/a |
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| Name | BDBM50186736 |
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| Synonyms: | CHEMBL380311 | L-1,4-dideoxy-4,4-difluorogulonojirimycin |
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| Type | Small organic molecule |
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| Emp. Form. | C6H11F2NO3 |
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| Mol. Mass. | 183.1532 |
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| SMILES | OC[C@@H]1NC[C@@H](O)[C@@H](O)C1(F)F |
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| Structure | 
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