| Reaction Details |
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 | Report a problem with these data |
| Target | Mas-related G-protein coupled receptor member X1 |
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| Ligand | BDBM50605953 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2253201 (CHEMBL5167411) |
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| EC50 | 206±n/a nM |
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| Citation |  Sharma, S; Peng, Q; Vadukoot, AK; Aretz, CD; Jensen, AA; Wallick, AI; Dong, X; Hopkins, CR Synthesis and Biological Characterization of a Series of 2-Sulfonamidebenzamides as Allosteric Modulators of MrgX1. ACS Med Chem Lett13:841-847 (2022) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Mas-related G-protein coupled receptor member X1 |
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| Name: | Mas-related G-protein coupled receptor member X1 |
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| Synonyms: | MRGPRX1 | MRGX1 | MRGX1_HUMAN | SNSR3 | SNSR4 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 36253.68 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_516621 |
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| Residue: | 322 |
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| Sequence: | MDPTISTLDTELTPINGTEETLCYKQTLSLTVLTCIVSLVGLTGNAVVLWLLGCRMRRNA
FSIYILNLAAADFLFLSGRLIYSLLSFISIPHTISKILYPVMMFSYFAGLSFLSAVSTER
CLSVLWPIWYRCHRPTHLSAVVCVLLWALSLLRSILEWMLCGFLFSGADSAWCQTSDFIT
VAWLIFLCVVLCGSSLVLLIRILCGSRKIPLTRLYVTILLTVLVFLLCGLPFGIQFFLFL
WIHVDREVLFCHVHLVSIFLSALNSSANPIIYFFVGSFRQRQNRQNLKLVLQRALQDASE
VDEGGGQLPEEILELSGSRLEQ
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| BDBM50605953 |
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| n/a |
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| Name | BDBM50605953 |
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| Synonyms: | CHEMBL5191110 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H18ClFN2O4S |
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| Mol. Mass. | 400.852 |
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| SMILES | CCOc1ccc(F)cc1NC(=O)c1cc(Cl)ccc1NS(=O)(=O)CC |
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| Structure | 
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