| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Equilibrative nucleoside transporter 1 |
|---|
| Ligand | BDBM50606918 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_2261595 (CHEMBL5216606) |
|---|
| IC50 | 19420±n/a nM |
|---|
| Citation |  Shahari, MSB; Dolzhenko, AV A closer look at N Eur J Med Chem241:0 (2022) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Equilibrative nucleoside transporter 1 |
|---|
| Name: | Equilibrative nucleoside transporter 1 |
|---|
| Synonyms: | ENT1 | Equilibrative NBMPR-sensitive nucleoside transporter | Equilibrative Nucleoside Transporter 1 (ENT1) | Equilibrative nitrobenzylmercaptopurine riboside-sensitive nucleoside transporter | Equilibrative nucleoside transporter 1 | Nucleoside transporter, es-type | S29A1_HUMAN | SLC29A1 | Solute carrier family 29 member 1 |
|---|
| Type: | Multi-pass membrane protein |
|---|
| Mol. Mass.: | 50225.92 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | n/a |
|---|
| Residue: | 456 |
|---|
| Sequence: | MTTSHQPQDRYKAVWLIFFMLGLGTLLPWNFFMTATQYFTNRLDMSQNVSLVTAELSKDA
QASAAPAAPLPERNSLSAIFNNVMTLCAMLPLLLFTYLNSFLHQRIPQSVRILGSLVAIL
LVFLITAILVKVQLDALPFFVITMIKIVLINSFGAILQGSLFGLAGLLPASYTAPIMSGQ
GLAGFFASVAMICAIASGSELSESAFGYFITACAVIILTIICYLGLPRLEFYRYYQQLKL
EGPGEQETKLDLISKGEEPRAGKEESGVSVSNSQPTNESHSIKAILKNISVLAFSVCFIF
TITIGMFPAVTVEVKSSIAGSSTWERYFIPVSCFLTFNIFDWLGRSLTAVFMWPGKDSRW
LPSLVLARLVFVPLLLLCNIKPRRYLTVVFEHDAWFIFFMAAFAFSNGYLASLCMCFGPK
KVKPAEAETAGAIMAFFLCLGLALGAVFSFLFRAIV
|
|
|
|---|
| BDBM50606918 |
|---|
| n/a |
|---|
| Name | BDBM50606918 |
|---|
| Synonyms: | CHEMBL5219061 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C24H24FN7 |
|---|
| Mol. Mass. | 429.4927 |
|---|
| SMILES | Nc1nc(CN2CCN(CC2)c2ccccc2F)nc(Nc2cccc3ccccc23)n1 |
|---|
| Structure | 
|
|---|
Search and Browse
