| Reaction Details |
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 | Report a problem with these data |
| Target | Equilibrative nucleoside transporter 2 |
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| Ligand | BDBM56941 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2261598 (CHEMBL5216609) |
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| IC50 | 570±n/a nM |
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| Citation |  Shahari, MSB; Dolzhenko, AV A closer look at N Eur J Med Chem241:0 (2022) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Equilibrative nucleoside transporter 2 |
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| Name: | Equilibrative nucleoside transporter 2 |
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| Synonyms: | 36 kDa nucleolar protein HNP36 | DER12 | DER12 | Delayed-early response protein 12 | ENT2 | Equilibrative NBMPR-insensitive nucleoside transporter | Equilibrative nitrobenzylmercaptopurine riboside-insensitive nucleoside transporter | Equilibrative nucleoside transporter 2 | HNP36 | Hydrophobic nucleolar protein, 36 kDa | Nucleoside transporter, ei-type | S29A2_HUMAN | SLC29A2 | Solute carrier family 29 member 2 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 50110.91 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_109695 |
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| Residue: | 456 |
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| Sequence: | MARGDAPRDSYHLVGISFFILGLGTLLPWNFFITAIPYFQARLAGAGNSTARILSTNHTG
PEDAFNFNNWVTLLSQLPLLLFTLLNSFLYQCVPETVRILGSLLAILLLFALTAALVKVD
MSPGPFFSITMASVCFINSFSAVLQGSLFGQLGTMPSTYSTLFLSGQGLAGIFAALAMLL
SMASGVDAETSALGYFITPCVGILMSIVCYLSLPHLKFARYYLANKSSQAQAQELETKAE
LLQSDENGIPSSPQKVALTLDLDLEKEPESEPDEPQKPGKPSVFTVFQKIWLTALCLVLV
FTVTLSVFPAITAMVTSSTSPGKWSQFFNPICCFLLFNIMDWLGRSLTSYFLWPDEDSRL
LPLLVCLRFLFVPLFMLCHVPQRSRLPILFPQDAYFITFMLLFAVSNGYLVSLTMCLAPR
QVLPHEREVAGALMTFFLALGLSCGASLSFLFKALL
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| BDBM56941 |
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| n/a |
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| Name | BDBM56941 |
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| Synonyms: | 6-[[4-(4-fluorophenyl)-1-piperazinyl]methyl]-N2-(3-methylphenyl)-1,3,5-triazine-2,4-diamine | 6-[[4-(4-fluorophenyl)piperazin-1-yl]methyl]-2-N-(3-methylphenyl)-1,3,5-triazine-2,4-diamine | 6-[[4-(4-fluorophenyl)piperazin-1-yl]methyl]-N2-(3-methylphenyl)-1,3,5-triazine-2,4-diamine | MLS000084209 | SMR000047961 | [4-amino-6-[[4-(4-fluorophenyl)piperazino]methyl]-s-triazin-2-yl]-(m-tolyl)amine | cid_666635 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H24FN7 |
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| Mol. Mass. | 393.4606 |
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| SMILES | Cc1cccc(Nc2nc(N)nc(CN3CCN(CC3)c3ccc(F)cc3)n2)c1 |
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| Structure | 
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