| Reaction Details |
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 | Report a problem with these data |
| Target | Equilibrative nucleoside transporter 2 |
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| Ligand | BDBM50606919 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2261598 (CHEMBL5216609) |
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| IC50 | 77120±n/a nM |
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| Citation |  Shahari, MSB; Dolzhenko, AV A closer look at N Eur J Med Chem241:0 (2022) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Equilibrative nucleoside transporter 2 |
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| Name: | Equilibrative nucleoside transporter 2 |
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| Synonyms: | 36 kDa nucleolar protein HNP36 | DER12 | DER12 | Delayed-early response protein 12 | ENT2 | Equilibrative NBMPR-insensitive nucleoside transporter | Equilibrative nitrobenzylmercaptopurine riboside-insensitive nucleoside transporter | Equilibrative nucleoside transporter 2 | HNP36 | Hydrophobic nucleolar protein, 36 kDa | Nucleoside transporter, ei-type | S29A2_HUMAN | SLC29A2 | Solute carrier family 29 member 2 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 50110.91 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_109695 |
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| Residue: | 456 |
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| Sequence: | MARGDAPRDSYHLVGISFFILGLGTLLPWNFFITAIPYFQARLAGAGNSTARILSTNHTG
PEDAFNFNNWVTLLSQLPLLLFTLLNSFLYQCVPETVRILGSLLAILLLFALTAALVKVD
MSPGPFFSITMASVCFINSFSAVLQGSLFGQLGTMPSTYSTLFLSGQGLAGIFAALAMLL
SMASGVDAETSALGYFITPCVGILMSIVCYLSLPHLKFARYYLANKSSQAQAQELETKAE
LLQSDENGIPSSPQKVALTLDLDLEKEPESEPDEPQKPGKPSVFTVFQKIWLTALCLVLV
FTVTLSVFPAITAMVTSSTSPGKWSQFFNPICCFLLFNIMDWLGRSLTSYFLWPDEDSRL
LPLLVCLRFLFVPLFMLCHVPQRSRLPILFPQDAYFITFMLLFAVSNGYLVSLTMCLAPR
QVLPHEREVAGALMTFFLALGLSCGASLSFLFKALL
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| BDBM50606919 |
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| n/a |
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| Name | BDBM50606919 |
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| Synonyms: | CHEMBL5219347 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H24FN7O |
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| Mol. Mass. | 409.46 |
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| SMILES | COc1ccc(Nc2nc(N)nc(CN3CCN(CC3)c3ccccc3F)n2)cc1 |
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| Structure | 
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