| Reaction Details |
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 | Report a problem with these data |
| Target | Glutathione hydrolase 1 proenzyme |
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| Ligand | BDBM50607259 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2262435 (CHEMBL5217446) |
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| Ki | 343000±n/a nM |
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| Citation |  Nguyen, L; Schultz, DC; Terzyan, SS; Rezaei, M; Songb, J; Li, C; You, Y; Hanigan, MH Design and evaluation of novel analogs of 2-amino-4-boronobutanoic acid (ABBA) as inhibitors of human gamma-glutamyl transpeptidase. Bioorg Med Chem73:0 (2022) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Glutathione hydrolase 1 proenzyme |
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| Name: | Glutathione hydrolase 1 proenzyme |
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| Synonyms: | GGT | GGT1 | GGT1_HUMAN | Gamma-glutamyltranspeptidase 1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 61413.51 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_543160 |
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| Residue: | 569 |
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| Sequence: | MKKKLVVLGLLAVVLVLVIVGLCLWLPSASKEPDNHVYTRAAVAADAKQCSKIGRDALRD
GGSAVDAAIAALLCVGLMNAHSMGIGGGLFLTIYNSTTRKAEVINAREVAPRLAFATMFN
SSEQSQKGGLSVAVPGEIRGYELAHQRHGRLPWARLFQPSIQLARQGFPVGKGLAAALEN
KRTVIEQQPVLCEVFCRDRKVLREGERLTLPQLADTYETLAIEGAQAFYNGSLTAQIVKD
IQAAGGIVTAEDLNNYRAELIEHPLNISLGDVVLYMPSAPLSGPVLALILNILKGYNFSR
ESVESPEQKGLTYHRIVEAFRFAYAKRTLLGDPKFVDVTEVVRNMTSEFFAAQLRAQISD
DTTHPISYYKPEFYTPDDGGTAHLSVVAEDGSAVSATSTINLYFGSKVRSPVSGILFNNE
MDDFSSPSITNEFGVPPSPANFIQPGKQPLSSMCPTIMVGQDGQVRMVVGAAGGTQITTA
TALAIIYNLWFGYDVKRAVEEPRLHNQLLPNVTTVERNIDQAVTAALETRHHHTQIASTF
IAVVQAIVRTAGGWAAASDSRKGGEPAGY
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| BDBM50607259 |
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| n/a |
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| Name | BDBM50607259 |
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| Synonyms: | CHEMBL5220006 |
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| Type | Small organic molecule |
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| Emp. Form. | C12H18BNO5 |
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| Mol. Mass. | 267.086 |
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| SMILES | COc1ccc(CN[C@H](CCB(O)O)C(O)=O)cc1 |r| |
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| Structure | 
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