| Reaction Details |
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 | Report a problem with these data |
| Target | Prostaglandin E2 receptor EP2 subtype |
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| Ligand | BDBM50403532 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2264278 |
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| Ki | 0.630000±n/a nM |
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| Citation |  Sluter, MN; Hou, R; Li, L; Yasmen, N; Yu, Y; Liu, J; Jiang, J EP2 Antagonists (2011-2021): A Decade's Journey from Discovery to Therapeutics. J Med Chem64:11816-11836 (2021) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Prostaglandin E2 receptor EP2 subtype |
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| Name: | Prostaglandin E2 receptor EP2 subtype |
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| Synonyms: | PE2R2_HUMAN | PGE receptor EP2 subtype | PTGER2 | Prostaglandin E2 | Prostaglandin E2 receptor | Prostaglandin E2 receptor EP4 subtype | Prostanoid EP2 Receptor |
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| Type: | Enzyme |
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| Mol. Mass.: | 39775.71 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P43116 |
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| Residue: | 358 |
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| Sequence: | MGNASNDSQSEDCETRQWLPPGESPAISSVMFSAGVLGNLIALALLARRWRGDVGCSAGR
RSSLSLFHVLVTELVFTDLLGTCLISPVVLASYARNQTLVALAPESRACTYFAFAMTFFS
LATMLMLFAMALERYLSIGHPYFYQRRVSRSGGLAVLPVIYAVSLLFCSLPLLDYGQYVQ
YCPGTWCFIRHGRTAYLQLYATLLLLLIVSVLACNFSVILNLIRMHRRSRRSRCGPSLGS
GRGGPGARRRGERVSMAEETDHLILLAIMTITFAVCSLPFTIFAYMNETSSRKEKWDLQA
LRFLSINSIIDPWVFAILRPPVLRLMRSVLCCRISLRTQDATQTSCSTQSDASKQADL
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| BDBM50403532 |
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| n/a |
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| Name | BDBM50403532 |
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| Synonyms: | CHEMBL5285583 |
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| Type | Small organic molecule |
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| Emp. Form. | C27H24N2O5 |
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| Mol. Mass. | 456.4899 |
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| SMILES | COc1ccc(cc1)C(=O)N1CCC(COc2ccc(cc2)-c2ccc(cc2)C#N)(C1)C(O)=O |
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| Structure | 
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