| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Monoglyceride lipase |
|---|
| Ligand | BDBM50191457 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_365397 (CHEMBL869118) |
|---|
| IC50 | 31000±n/a nM |
|---|
| Citation |  Saario, SM; Poso, A; Juvonen, RO; Järvinen, T; Salo-Ahen, OM Fatty acid amide hydrolase inhibitors from virtual screening of the endocannabinoid system. J Med Chem49:4650-6 (2006) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Monoglyceride lipase |
|---|
| Name: | Monoglyceride lipase |
|---|
| Synonyms: | MAGL | MGLL_RAT | Mgl2 | Mgll | Monoacylglycerol lipase | Monoglyceride lipase | Monoglyceride lipase (MGL) |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 33505.38 |
|---|
| Organism: | Rattus norvegicus (Rat) |
|---|
| Description: | Q8R431 |
|---|
| Residue: | 303 |
|---|
| Sequence: | MPEASSPRRTPQNVPYQDLPHLVNADGQYLFCRYWKPSGTPKALIFVSHGAGEHCGRYDE
LAQMLKRLDMLVFAHDHVGHGQSEGERMVVSDFQVFVRDLLQHVNTVQKDYPEVPVFLLG
HSMGGAISILAAAERPTHFSGMILISPLILANPESASTLKVLAAKLLNFVLPNISLGRID
SSVLSRNKSEVDLYNSDPLICHAGVKVCFGIQLLNAVSRVERAMPRLTLPFLLLQGSADR
LCDSKGAYLLMESSPSQDKTLKMYEGAYHVLHKELPEVTNSVLHEINTWVSHRIAVAGAR
CLP
|
|
|
|---|
| BDBM50191457 |
|---|
| n/a |
|---|
| Name | BDBM50191457 |
|---|
| Synonyms: | 4-(thiazol-2-yl)phenyl butylcarbamate | CHEMBL376748 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C14H16N2O2S |
|---|
| Mol. Mass. | 276.354 |
|---|
| SMILES | CCCCNC(=O)Oc1ccc(cc1)-c1nccs1 |
|---|
| Structure | 
|
|---|
Search and Browse
