| Reaction Details |
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 | Report a problem with these data |
| Target | Cyclin-dependent kinase 14 |
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| Ligand | BDBM50404389 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2264714 |
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| IC50 | >1200±n/a nM |
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| Citation |  Huang, Z; Wang, T; Wang, C; Fan, Y CDK9 inhibitors in cancer research. RSC Med Chem13:688-710 (2022) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Cyclin-dependent kinase 14 |
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| Name: | Cyclin-dependent kinase 14 |
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| Synonyms: | CDK14 | CDK14_HUMAN | KIAA0834 | PFTK1 | Serine/threonine-protein kinase PFTAIRE-1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 53075.39 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_774550 |
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| Residue: | 469 |
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| Sequence: | MCDLIEPQPAEKIGKMKKLRRTLSESFSRIALKKDDTTFDEICVTKMSTRNCQGMDSVIK
PLDTIPEDKKVRVQRTQSTFDPFEKPANQVKRVHSENNACINFKTSSTGKESPKVRRHSS
PSSPTSPKFGKADSYEKLEKLGEGSYATVYKGKSKVNGKLVALKVIRLQEEEGTPFTAIR
EASLLKGLKHANIVLLHDIIHTKETLTLVFEYVHTDLCQYMDKHPGGLHPDNVKLFLFQL
LRGLSYIHQRYILHRDLKPQNLLISDTGELKLADFGLARAKSVPSHTYSNEVVTLWYRPP
DVLLGSTEYSTCLDMWGVGCIFVEMIQGVAAFPGMKDIQDQLERIFLVLGTPNEDTWPGV
HSLPHFKPERFTLYSSKNLRQAWNKLSYVNHAEDLASKLLQCSPKNRLSAQAALSHEYFS
DLPPRLWELTDMSSIFTVPNVRLQPEAGESMRAFGKNNSYGKSLSNSKH
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| BDBM50404389 |
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| n/a |
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| Name | BDBM50404389 |
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| Synonyms: | CHEMBL5285499 |
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| Type | Small organic molecule |
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| Emp. Form. | C14H21N5 |
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| Mol. Mass. | 259.35 |
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| SMILES | CCCc1cc(N[C@@H]2CC[C@@H](N)C2)n2nccc2n1 |r| |
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| Structure | 
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