| Reaction Details |
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 | Report a problem with these data |
| Target | Photoreceptor-specific nuclear receptor |
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| Ligand | BDBM50192208 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_401901 (CHEMBL906904) |
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| EC50 | 141±n/a nM |
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| Citation |  Wolkenberg, SE; Zhao, Z; Kapitskaya, M; Webber, AL; Petrukhin, K; Tang, YS; Dean, DC; Hartman, GD; Lindsley, CW Identification of potent agonists of photoreceptor-specific nuclear receptor (NR2E3) and preparation of a radioligand. Bioorg Med Chem Lett16:5001-4 (2006) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Photoreceptor-specific nuclear receptor |
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| Name: | Photoreceptor-specific nuclear receptor |
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| Synonyms: | NR2E3 | NR2E3_HUMAN | PNR | RNR | photoreceptor-specific nuclear receptor |
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| Type: | PROTEIN |
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| Mol. Mass.: | 44699.83 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_401901 |
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| Residue: | 410 |
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| Sequence: | METRPTALMSSTVAAAAPAAGAASRKESPGRWGLGEDPTGVSPSLQCRVCGDSSSGKHYG
IYACNGCSGFFKRSVRRRLIYRCQVGAGMCPVDKAHRNQCQACRLKKCLQAGMNQDAVQN
ERQPRSTAQVHLDSMESNTESRPESLVAPPAPAGRSPRGPTPMSAARALGHHFMASLITA
ETCAKLEPEDADENIDVTSNDPEFPSSPYSSSSPCGLDSIHETSARLLFMAVKWAKNLPV
FSSLPFRDQVILLEEAWSELFLLGAIQWSLPLDSCPLLAPPEASAAGGAQGRLTLASMET
RVLQETISRFRALAVDPTEFACMKALVLFKPETRGLKDPEHVEALQDQSQVMLSQHSKAH
HPSQPVRFGKLLLLLPSLRFITAERIELLFFRKTIGNTPMEKLLCDMFKN
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| BDBM50192208 |
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| n/a |
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| Name | BDBM50192208 |
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| Synonyms: | 2-chloro-N-(4-(5-(cyclopropanecarboxamido)-1H-benzo[d]imidazol-2-yl)phenyl)benzamide | CHEMBL386138 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H19ClN4O2 |
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| Mol. Mass. | 430.886 |
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| SMILES | Clc1ccccc1C(=O)Nc1ccc(cc1)-c1nc2ccc(NC(=O)C3CC3)cc2[nH]1 |
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| Structure | 
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