| Reaction Details |
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 | Report a problem with these data |
| Target | Photoreceptor-specific nuclear receptor |
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| Ligand | BDBM50192213 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_401902 (CHEMBL906905) |
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| EC50 | 4100±n/a nM |
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| Citation |  Wolkenberg, SE; Zhao, Z; Kapitskaya, M; Webber, AL; Petrukhin, K; Tang, YS; Dean, DC; Hartman, GD; Lindsley, CW Identification of potent agonists of photoreceptor-specific nuclear receptor (NR2E3) and preparation of a radioligand. Bioorg Med Chem Lett16:5001-4 (2006) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Photoreceptor-specific nuclear receptor |
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| Name: | Photoreceptor-specific nuclear receptor |
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| Synonyms: | NR2E3 | NR2E3_HUMAN | PNR | RNR | photoreceptor-specific nuclear receptor |
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| Type: | PROTEIN |
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| Mol. Mass.: | 44699.83 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_401901 |
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| Residue: | 410 |
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| Sequence: | METRPTALMSSTVAAAAPAAGAASRKESPGRWGLGEDPTGVSPSLQCRVCGDSSSGKHYG
IYACNGCSGFFKRSVRRRLIYRCQVGAGMCPVDKAHRNQCQACRLKKCLQAGMNQDAVQN
ERQPRSTAQVHLDSMESNTESRPESLVAPPAPAGRSPRGPTPMSAARALGHHFMASLITA
ETCAKLEPEDADENIDVTSNDPEFPSSPYSSSSPCGLDSIHETSARLLFMAVKWAKNLPV
FSSLPFRDQVILLEEAWSELFLLGAIQWSLPLDSCPLLAPPEASAAGGAQGRLTLASMET
RVLQETISRFRALAVDPTEFACMKALVLFKPETRGLKDPEHVEALQDQSQVMLSQHSKAH
HPSQPVRFGKLLLLLPSLRFITAERIELLFFRKTIGNTPMEKLLCDMFKN
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| BDBM50192213 |
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| n/a |
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| Name | BDBM50192213 |
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| Synonyms: | 2-chloro-N-(2-(1-(4-fluorophenyl)-1H-pyrazol-4-yl)-1H-benzo[d]imidazol-5-yl)benzamide | CHEMBL384066 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H15ClFN5O |
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| Mol. Mass. | 431.85 |
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| SMILES | Fc1ccc(cc1)-n1cc(cn1)-c1nc2ccc(NC(=O)c3ccccc3Cl)cc2[nH]1 |
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| Structure | 
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