| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Toll-like receptor 2 |
|---|
| Ligand | BDBM50406600 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_2266642 |
|---|
| Ki | 22±n/a nM |
|---|
| Citation |  Kaur, A; Kaushik, D; Piplani, S; Mehta, SK; Petrovsky, N; Salunke, DB TLR2 Agonistic Small Molecules: Detailed Structure-Activity Relationship, Applications, and Future Prospects. J Med Chem64:233-278 (2021) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Toll-like receptor 2 |
|---|
| Name: | Toll-like receptor 2 |
|---|
| Synonyms: | TIL4 | TLR2 | TLR2_HUMAN | Toll-like receptor 2 | Toll-like receptor 2 (TLR2) |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 89837.58 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | O60603 |
|---|
| Residue: | 784 |
|---|
| Sequence: | MPHTLWMVWVLGVIISLSKEESSNQASLSCDRNGICKGSSGSLNSIPSGLTEAVKSLDLS
NNRITYISNSDLQRCVNLQALVLTSNGINTIEEDSFSSLGSLEHLDLSYNYLSNLSSSWF
KPLSSLTFLNLLGNPYKTLGETSLFSHLTKLQILRVGNMDTFTKIQRKDFAGLTFLEELE
IDASDLQSYEPKSLKSIQNVSHLILHMKQHILLLEIFVDVTSSVECLELRDTDLDTFHFS
ELSTGETNSLIKKFTFRNVKITDESLFQVMKLLNQISGLLELEFDDCTLNGVGNFRASDN
DRVIDPGKVETLTIRRLHIPRFYLFYDLSTLYSLTERVKRITVENSKVFLVPCLLSQHLK
SLEYLDLSENLMVEEYLKNSACEDAWPSLQTLILRQNHLASLEKTGETLLTLKNLTNIDI
SKNSFHSMPETCQWPEKMKYLNLSSTRIHSVTGCIPKTLEILDVSNNNLNLFSLNLPQLK
ELYISRNKLMTLPDASLLPMLLVLKISRNAITTFSKEQLDSFHTLKTLEAGGNNFICSCE
FLSFTQEQQALAKVLIDWPANYLCDSPSHVRGQQVQDVRLSVSECHRTALVSGMCCALFL
LILLTGVLCHRFHGLWYMKMMWAWLQAKRKPRKAPSRNICYDAFVSYSERDAYWVENLMV
QELENFNPPFKLCLHKRDFIPGKWIIDNIIDSIEKSHKTVFVLSENFVKSEWCKYELDFS
HFRLFDENNDAAILILLEPIEKKAIPQRFCKLRKIMNTKTYLEWPMDEAQREGFWVNLRA
AIKS
|
|
|
|---|
| BDBM50406600 |
|---|
| n/a |
|---|
| Name | BDBM50406600 |
|---|
| Synonyms: | CHEMBL5267159 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C54H103N7O17S |
|---|
| Mol. Mass. | 1154.497 |
|---|
| SMILES | CCCCCCCCCCCCCCCC(=O)OCCSC[C@H](NC(=O)COCC(=O)NCCCOCCOCCOCCCNC)C(=O)NCC(=O)N[C@H](CO)C(=O)COCC(=O)NCCCOCCOCCOCCCN |r| |
|---|
| Structure | 
|
|---|
Search and Browse
