| Reaction Details |
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 | Report a problem with these data |
| Target | 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase |
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| Ligand | BDBM50407454 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2266976 |
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| IC50 | 49±n/a nM |
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| Citation |  Phull, MS; Jadav, SS; Gundla, R; Mainkar, PS A perspective on medicinal chemistry approaches towards adenomatous polyposis coli and Wnt signal based colorectal cancer inhibitors. Eur J Med Chem212:0 (2021) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase |
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| Name: | 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase |
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| Synonyms: | 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase/Delta(24)-sterol reductase | 3-beta-hydroxysteroid-delta(8),delta(7)-isomerase | Anti-estrogen binding site (AEBS) | Cholestenol Delta-isomerase | D8-D7 sterol isomerase | Delta(8)-Delta(7) sterol isomerase | EBP | EBP_HUMAN | Emopamil-binding protein |
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| Type: | PROTEIN |
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| Mol. Mass.: | 26358.51 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_873432 |
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| Residue: | 230 |
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| Sequence: | MTTNAGPLHPYWPQHLRLDNFVPNDRPTWHILAGLFSVTGVLVVTTWLLSGRAAVVPLGT
WRRLSLCWFAVCGFIHLVIEGWFVLYYEDLLGDQAFLSQLWKEYAKGDSRYILGDNFTVC
METITACLWGPLSLWVVIAFLRQHPLRFILQLVVSVGQIYGDVLYFLTEHRDGFQHGELG
HPLYFWFYFVFMNALWLVLPGVLVLDAVKHLTHAQSTLDAKATKAKSKKN
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| BDBM50407454 |
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| n/a |
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| Name | BDBM50407454 |
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| Synonyms: | CHEMBL5281526 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H32N2O2S |
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| Mol. Mass. | 412.588 |
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| SMILES | CC1CCN(CC1)C1CCN(CC1)S(=O)(=O)c1ccc(cc1)-c1ccc(C)cc1 |
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| Structure | 
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