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Target5-hydroxytryptamine receptor 6
LigandBDBM30707
Substrate/Competitorn/a
Meas. Tech.ChEMBL_424391 (CHEMBL911322)
Ki 13±n/a nM
Citation Kolanos, R; Dukat, M; Roth, BL; Glennon, RA Interaction of N1-unsubstituted and N1-benzenesulfonyltryptamines at h5-HT6 receptors. Bioorg Med Chem Lett16:5832-5 (2006) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
5-hydroxytryptamine receptor 6
Name:5-hydroxytryptamine receptor 6
Synonyms:5-HT-6 | 5-HT6 | 5-hydroxytryptamine receptor 6 (5-HT-6) | 5-hydroxytryptamine receptor 6 (5-HT6R) | 5-hydroxytryptamine receptor 6 (5HT6) | 5HT6R_HUMAN | HTR6 | Serotonin (5-HT3) receptor | Serotonin 6 (5-HT6) receptor | Serotonin Receptor 6
Type:G Protein-Coupled Receptor (GPCR)
Mol. Mass.:46968.43
Organism:Homo sapiens (Human)
Description:P50406
Residue:440
Sequence:
MVPEPGPTANSTPAWGAGPPSAPGGSGWVAAALCVVIALTAAANSLLIALICTQPALRNT
SNFFLVSLFTSDLMVGLVVMPPAMLNALYGRWVLARGLCLLWTAFDVMCCSASILNLCLI
SLDRYLLILSPLRYKLRMTPLRALALVLGAWSLAALASFLPLLLGWHELGHARPPVPGQC
RLLASLPFVLVASGLTFFLPSGAICFTYCRILLAARKQAVQVASLTTGMASQASETLQVP
RTPRPGVESADSRRLATKHSRKALKASLTLGILLGMFFVTWLPFFVANIVQAVCDCISPG
LFDVLTWLGYCNSTMNPIIYPLFMRDFKRALGRFLPCPRCPRERQASLASPSLRTSHSGP
RPGLSLQQVLPLPLPPDSDSDSDAGSGGSSGLRLTAQLLLPGEATQDPPLPTRAAAAVNF
FNIDPAEPELRPHPLGIPTN
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  Blast E-value cutoff:
BDBM30707
n/a
NameBDBM30707
Synonyms:2-(5-methoxy-1H-indol-3-yl)-N,N-dimethyl-ethanamine | 2-(5-methoxy-1H-indol-3-yl)-N,N-dimethylethanamine | 2-(5-methoxy-1H-indol-3-yl)ethyl-dimethyl-amine | 3-(2-DIMETHYLAMINOETHYL)-5-METHOXYINDOLE | CHEMBL7257 | MLS000069438 | Methoxydimethyltryptamines | SMR000059066 | WO2023019367, Compound 5-MeO-DMT | cid_1832
TypeSmall organic molecule
Emp. Form.C13H18N2O
Mol. Mass.218.2948
SMILESCOc1ccc2[nH]cc(CCN(C)C)c2c1
Structure
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