| Reaction Details |
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 | Report a problem with these data |
| Target | Enoyl-[acyl-carrier-protein] reductase [NADH] FabI |
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| Ligand | BDBM50481813 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2271376 |
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| IC50 | 340±n/a nM |
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| Citation |  Rana, P; Ghouse, SM; Akunuri, R; Madhavi, YV; Chopra, S; Nanduri, S FabI (enoyl acyl carrier protein reductase) - A potential broad spectrum therapeutic target and its inhibitors. Eur J Med Chem208:0 (2020) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Enoyl-[acyl-carrier-protein] reductase [NADH] FabI |
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| Name: | Enoyl-[acyl-carrier-protein] reductase [NADH] FabI |
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| Synonyms: | Enoyl - (acyl carrier protein) reductase | Enoyl-ACP Reductase (FabI) | Enoyl-[acyl-carrier-protein] reductase | Enoyl-acyl carrier protein reductase (FabI) | FABI_ECOLI | NADH-dependent enoyl-ACP reductase | envM | fabI |
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| Type: | Enzyme |
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| Mol. Mass.: | 27861.12 |
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| Organism: | Escherichia coli |
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| Description: | n/a |
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| Residue: | 262 |
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| Sequence: | MGFLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIV
LQCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDIS
SYSFVAMAKACRSMLNPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPE
GVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSAGI
SGEVVHVDGGFSIAAMNELELK
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| BDBM50481813 |
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| n/a |
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| Name | BDBM50481813 |
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| Synonyms: | CHEMBL5274978 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H16Cl3NO |
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| Mol. Mass. | 392.706 |
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| SMILES | Cc1cccc(Cl)c1Cc1c(Cl)n(Cc2cccc(Cl)c2)ccc1=O |
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| Structure | 
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