| Reaction Details |
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 | Report a problem with these data |
| Target | Urea transporter 1 |
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| Ligand | BDBM50134204 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2271898 |
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| IC50 | 1000±n/a nM |
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| Citation |  Titko, T; Perekhoda, L; Drapak, I; Tsapko, Y Modern trends in diuretics development. Eur J Med Chem208:0 (2020) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Urea transporter 1 |
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| Name: | Urea transporter 1 |
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| Synonyms: | Slc14a1 | Solute carrier family 14 member 1 | UT-B | UT1_MOUSE | Urea transporter B | Urea transporter, erythrocyte |
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| Type: | PROTEIN |
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| Mol. Mass.: | 42130.98 |
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| Organism: | Mus musculus |
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| Description: | ChEMBL_964780 |
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| Residue: | 384 |
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| Sequence: | MEDSPTMVKVDRGENQILSCRGRRCGFKVLGYVTGDMKEFANWLKDKPVVLQFMDWILRG
ISQVVFVSNPISGILILVGLLVQNPWWALCGCVGTVVSTLTALLLSQDRSAIAAGLQGYN
ATLVGILMAVFSNKGDYFWWLIFPVSAMSMTCPVFSSALSSVLSKWDLPVFTLPFNMALS
MYLSATGHYNTFFPSKLFTPVSSVPNITWSELSALELLKSLPVGVGQIYGCDNPWTGGIF
LCAILLSSPLMCLHAAIGSLLGVIAGLSLAAPFEDIYFGLWGFNSSLACIAIGGMFMALT
WQTHLLALACALFTAYFGACMAHLMAVVHLPACTWSFCLATLLFLLLTTKNPNIYRMPLS
KVTYSEENRIFYLQNKKRMVESPL
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| BDBM50134204 |
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| n/a |
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| Name | BDBM50134204 |
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| Synonyms: | CHEMBL3740772 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H14N2O3 |
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| Mol. Mass. | 294.3047 |
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| SMILES | CC(=O)Nc1ccc2-c3ccc(NC(C)=O)cc3C(=O)c2c1 |
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| Structure | 
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