| Reaction Details |
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 | Report a problem with these data |
| Target | D-3-phosphoglycerate dehydrogenase |
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| Ligand | BDBM50232880 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2272272 |
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| Kd | 6500000±n/a nM |
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| Citation |  Zhao, JY; Feng, KR; Wang, F; Zhang, JW; Cheng, JF; Lin, GQ; Gao, D; Tian, P A retrospective overview of PHGDH and its inhibitors for regulating cancer metabolism. Eur J Med Chem217:0 (2021) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| D-3-phosphoglycerate dehydrogenase |
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| Name: | D-3-phosphoglycerate dehydrogenase |
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| Synonyms: | D-3-phosphoglycerate dehydrogenase | PGDH3 | PHGDH | Phosphoglycerate dehydrogenase (PHGDH) | SERA_HUMAN |
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| Type: | Protein |
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| Mol. Mass.: | 56650.89 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 533 |
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| Sequence: | MAFANLRKVLISDSLDPCCRKILQDGGLQVVEKQNLSKEELIAELQDCEGLIVRSATKVT
ADVINAAEKLQVVGRAGTGVDNVDLEAATRKGILVMNTPNGNSLSAAELTCGMIMCLARQ
IPQATASMKDGKWERKKFMGTELNGKTLGILGLGRIGREVATRMQSFGMKTIGYDPIISP
EVSASFGVQQLPLEEIWPLCDFITVHTPLLPSTTGLLNDNTFAQCKKGVRVVNCARGGIV
DEGALLRALQSGQCAGAALDVFTEEPPRDRALVDHENVISCPHLGASTKEAQSRCGEEIA
VQFVDMVKGKSLTGVVNAQALTSAFSPHTKPWIGLAEALGTLMRAWAGSPKGTIQVITQG
TSLKNAGNCLSPAVIVGLLKEASKQADVNLVNAKLLVKEAGLNVTTSHSPAAPGEQGFGE
CLLAVALAGAPYQAVGLVQGTTPVLQGLNGAVFRPEVPLRRDLPLLLFRTQTSDPAMLPT
MIGLLAEAGVRLLSYQTSLVSDGETWHVMGISSLLPSLEAWKQHVTEAFQFHF
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| BDBM50232880 |
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| n/a |
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| Name | BDBM50232880 |
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| Synonyms: | Benzo[D]Isoxazol-3-Ol | CHEMBL444173 |
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| Type | Small organic molecule |
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| Emp. Form. | C7H5NO2 |
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| Mol. Mass. | 135.1201 |
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| SMILES | Oc1noc2ccccc12 |
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| Structure | 
|
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