| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Melatonin receptor type 1A |
|---|
| Ligand | BDBM23416 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_2272288 |
|---|
| IC50 | 25800±n/a nM |
|---|
| Citation |  Hügel, HM; de Silva, NH; Siddiqui, A; Blanch, E; Lingham, A Natural spirocyclic alkaloids and polyphenols as multi target dementia leads. Bioorg Med Chem43:0 (2021) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Melatonin receptor type 1A |
|---|
| Name: | Melatonin receptor type 1A |
|---|
| Synonyms: | MTNR1A | MTNR1A protein | MTR1A_HUMAN | Mel-1A-R | Mel1a melatonin receptor | Melatonin 1A | Melatonin receptor | Melatonin receptor 1A | Melatonin receptor type 1 (MT1) | Melatonin receptor type 1A |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 39392.94 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P48039 |
|---|
| Residue: | 350 |
|---|
| Sequence: | MQGNGSALPNASQPVLRGDGARPSWLASALACVLIFTIVVDILGNLLVILSVYRNKKLRN
AGNIFVVSLAVADLVVAIYPYPLVLMSIFNNGWNLGYLHCQVSGFLMGLSVIGSIFNITG
IAINRYCYICHSLKYDKLYSSKNSLCYVLLIWLLTLAAVLPNLRAGTLQYDPRIYSCTFA
QSVSSAYTIAVVVFHFLVPMIIVIFCYLRIWILVLQVRQRVKPDRKPKLKPQDFRNFVTM
FVVFVLFAICWAPLNFIGLAVASDPASMVPRIPEWLFVASYYMAYFNSCLNAIIYGLLNQ
NFRKEYRRIIVSLCTARVFFVDSSNDVADRVKWKPSPLMTNNNVVKVDSV
|
|
|
|---|
| BDBM23416 |
|---|
| n/a |
|---|
| Name | BDBM23416 |
|---|
| Synonyms: | α-CA inhibitor, 3 | (+)-Catechin | (2R,3S)-2-(3,4-dihydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-3,5,7-triol | CHEMBL311498 | Catechin | D-Catechin |
|---|
| Type | Flavonol |
|---|
| Emp. Form. | C15H14O6 |
|---|
| Mol. Mass. | 290.2681 |
|---|
| SMILES | O[C@H]1Cc2c(O)cc(O)cc2O[C@@H]1c1ccc(O)c(O)c1 |r| |
|---|
| Structure | 
|
|---|
Search and Browse
