| Reaction Details |
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 | Report a problem with these data |
| Target | Cell division protein FtsZ |
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| Ligand | BDBM50201769 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2273984 |
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| IC50 | 37500±n/a nM |
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| Citation |  Buroni, S; Makarov, V; Scoffone, VC; Trespidi, G; Riccardi, G; Chiarelli, LR The cell division protein FtsZ as a cellular target to hit cystic fibrosis pathogens. Eur J Med Chem190:0 (2020) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Cell division protein FtsZ |
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| Name: | Cell division protein FtsZ |
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| Synonyms: | FTSZ_STAAU | ftsZ |
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| Type: | Protein |
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| Mol. Mass.: | 41023.36 |
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| Organism: | Staphylococcus aureus |
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| Description: | P0A031 |
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| Residue: | 390 |
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| Sequence: | MLEFEQGFNHLATLKVIGVGGGGNNAVNRMIDHGMNNVEFIAINTDGQALNLSKAESKIQ
IGEKLTRGLGAGANPEIGKKAAEESREQIEDAIQGADMVFVTSGMGGGTGTGAAPVVAKI
AKEMGALTVGVVTRPFSFEGRKRQTQAAAGVEAMKAAVDTLIVIPNDRLLDIVDKSTPMM
EAFKEADNVLRQGVQGISDLIAVSGEVNLDFADVKTIMSNQGSALMGIGVSSGENRAVEA
AKKAISSPLLETSIVGAQGVLMNITGGESLSLFEAQEAADIVQDAADEDVNMIFGTVINP
ELQDEIVVTVIATGFDDKPTSHGRKSGSTGFGTSVNTSSNATSKDESFTSNSSNAQATDS
VSERTHTTKEDDIPSFIRNREERRSRRTRR
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| BDBM50201769 |
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| n/a |
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| Name | BDBM50201769 |
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| Synonyms: | CHEMBL3416823 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H31N5 |
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| Mol. Mass. | 365.515 |
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| SMILES | [H][C@@]12CCN(C[C@@H]1c1cc(nc(n1)-c1ccncc1)C(CC)CC)[C@@H](CN)C2 |r| |
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| Structure | 
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