| Reaction Details |
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 | Report a problem with these data |
| Target | Monocarboxylate transporter 1 |
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| Ligand | BDBM50608634 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2274356 |
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| IC50 | >5000±n/a nM |
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| Citation |  Puri, S; Juvale, K Monocarboxylate transporter 1 and 4 inhibitors as potential therapeutics for treating solid tumours: A review with structure-activity relationship insights. Eur J Med Chem199:0 (2020) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Monocarboxylate transporter 1 |
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| Name: | Monocarboxylate transporter 1 |
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| Synonyms: | MCT 1 | MOT1_RAT | Mct1 | Monocarboxylate transporter 1 | Monocarboxylate transporter 1 (MCT1) | Slc16a1 | Solute carrier family 16 member 1 |
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| Type: | Enzyme |
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| Mol. Mass.: | 53245.17 |
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| Organism: | Rattus norvegicus (Rat) |
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| Description: | P53987 |
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| Residue: | 494 |
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| Sequence: | MPPAIGGPVGYTPPDGGWGWAVVVGAFISIGFSYAFPKSITVFFKEIEIIFSATTSEVSW
ISSIMLAVMYAGGPISSILVNKYGSRPVMIAGGCLSGCGLIAASFCNTVQELYFCIGVIG
GLGLAFNLNPALTMIGKYFYKKRPLANGLAMAGSPVFLSTLAPLNQAFFGIFGWRGSFLI
LGGLLLNCCVAGSLMRPIGPQQGKVEKLKSKESLQEAGKSDANTDLIGGSPKGEKLSVFQ
TVNKFLDLSLFTHRGFLLYLSGNVVMFFGLFTPLVFLSNYGKSKHFSSEKSAFLLSILAF
VDMVARPSMGLAANTRWIRPRVQYFFAASVVANGVCHLLAPLSTTYVGFCIYAGVFGFAF
GWLSSVLFETLMDLVGPQRFSSAVGLVTIVECCPVLLGPPLLGRLNDMYGDYKYTYWACG
VILIIAGLYLFIGMGINYRLVAKEQKAEEKKRDGKEDETSTDVDEKPKKTMKETQSPAPL
QNSSGDPAEEESPV
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| BDBM50608634 |
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| n/a |
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| Name | BDBM50608634 |
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| Synonyms: | CHEMBL5280998 |
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| Type | Small organic molecule |
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| Emp. Form. | C12H11NO4 |
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| Mol. Mass. | 233.22 |
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| SMILES | OCCOc1ccc(\C=C(/C#N)C(O)=O)cc1 |
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| Structure | 
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