| Reaction Details |
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 | Report a problem with these data |
| Target | C-X-C chemokine receptor type 3 |
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| Ligand | BDBM50198394 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_437678 (CHEMBL905953) |
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| Ki | 400±n/a nM |
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| Citation |  Allen, DR; Bolt, A; Chapman, GA; Knight, RL; Meissner, JW; Owen, DA; Watson, RJ Identification and structure-activity relationships of 1-aryl-3-piperidin-4-yl-urea derivatives as CXCR3 receptor antagonists. Bioorg Med Chem Lett17:697-701 (2007) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| C-X-C chemokine receptor type 3 |
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| Name: | C-X-C chemokine receptor type 3 |
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| Synonyms: | CXCR3_MOUSE | Cmkar3 | Cxcr3 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 41020.84 |
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| Organism: | Mus musculus |
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| Description: | ChEMBL_560734 |
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| Residue: | 367 |
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| Sequence: | MYLEVSERQVLDASDFAFLLENSTSPYDYGENESDFSDSPPCPQDFSLNFDRTFLPALYS
LLFLLGLLGNGAVAAVLLSQRTALSSTDTFLLHLAVADVLLVLTLPLWAVDAAVQWVFGP
GLCKVAGALFNINFYAGAFLLACISFDRYLSIVHATQIYRRDPRVRVALTCIVVWGLCLL
FALPDFIYLSANYDQRLNATHCQYNFPQVGRTALRVLQLVAGFLLPLLVMAYCYAHILAV
LLVSRGQRRFRAMRLVVVVVAAFAVCWTPYHLVVLVDILMDVGVLARNCGRESHVDVAKS
VTSGMGYMHCCLNPLLYAFVGVKFREQMWMLFTRLGRSDQRGPQRQPSSSRRESSWSETT
EASYLGL
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| BDBM50198394 |
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| n/a |
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| Name | BDBM50198394 |
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| Synonyms: | (E)-1-(1-(cyclooctenylmethyl)piperidin-4-yl)-3-(naphthalen-2-yl)urea | 1-(1-(cyclooctenylmethyl)piperidin-4-yl)-3-(naphthalen-2-yl)urea | CHEMBL244610 |
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| Type | Small organic molecule |
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| Emp. Form. | C25H33N3O |
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| Mol. Mass. | 391.549 |
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| SMILES | O=C(NC1CCN(C\C2=C\CCCCCC2)CC1)Nc1ccc2ccccc2c1 |t:8| |
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| Structure | 
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