| Reaction Details |
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 | Report a problem with these data |
| Target | Peptidase |
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| Ligand | BDBM50611996 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2285381 |
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| Kd | 18400±n/a nM |
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| Citation |  Shalaby, MW; Dokla, EME; Serya, RAT; Abouzid, KAM Penicillin binding protein 2a: An overview and a medicinal chemistry perspective. Eur J Med Chem199:0 (2020) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Peptidase |
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| Name: | Peptidase |
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| Synonyms: | MecA | Pbp2a | Penicillin binding protein 2 prime | Penicillin binding protein 2' | Penicillin binding protein 2a (PBP2a) | Penicillin-binding protein 2 prime | Penicillin-binding protein 2' |
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| Type: | PROTEIN |
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| Mol. Mass.: | 76113.18 |
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| Organism: | Staphylococcus aureus |
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| Description: | ChEMBL_677175 |
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| Residue: | 668 |
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| Sequence: | MKKIKIVPLILIVVVVGFGIYFYASKDKEINNTIDAIEDKNFKQVYKDSSYISKSDNGEV
EMTERPIKIYNSLGVKDINIQDRKIKKVSKNKKRVDAQYKIKTNYGNIDRNVQFNFVKED
GMWKLDWDHSVIIPGMQKDQSIHIENLKSERGKILDRNNVELANTGTAYEIGIVPKNVSK
KDYKAIAKELSISEDYIKQQMDQNWVQDDTFVPLKTVKKMDEYLSDFAKKFHLTTNETES
RNYPLGKATSHLLGYVGPINSEELKQKEYKGYKDDAVIGKKGLEKLYDKKLQHEDGYRVT
IVDDNSNTIAHTLIEKKKKDGKDIQLTIDAKVQKSIYNNMKNDYGSGTAIHPQTGELLAL
VSTPSYDVYPFMYGMSNEEYNKLTEDKKEPLLNKFQITTSPGSTQKILTAMIGLNNKTLD
DKTSYKIDGKGWQKDKSWGGYNVTRYEVVNGNIDLKQAIESSDNIFFARVALELGSKKFE
KGMKKLGVGEDIPSDYPFYNAQISNKNLDNEILLADSGYGQGEILINPVQILSIYSALEN
NGNINAPHLLKDTKNKVWKKNIISKENINLLTDGMQQVVNKTHKEDIYRSYANLIGKSGT
AELKMKQGETGRQIGWFISYDKDNPNMMMAINVKDVQDKGMASYNAKISGKVYDELYENG
NKKYDIDE
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| BDBM50611996 |
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| n/a |
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| Name | BDBM50611996 |
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| Synonyms: | CHEMBL5274536 |
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| Type | Small organic molecule |
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| Emp. Form. | C25H30O6 |
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| Mol. Mass. | 426.5021 |
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| SMILES | [H][C@@]12CC[C@@]34C[C@@]5(C)C=C(C(=O)OC)[C@@]33CO[C@@]4(O[C@@]3(C)CC5=O)[C@@]1([H])C=CC(=O)C2(C)C |r,c:31,t:8,TLB:8:6:17.18:14,23:22:17.18:14,7:6:17.18:14,10:9:19.22.21:4.5,3:4:9.8:19.22.21,18:19:9.8:4.5,THB:23:22:9.8:4.5,17:4:9.8:19.22.21| |
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| Structure | 
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