| Reaction Details |
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 | Report a problem with these data |
| Target | Carbonic anhydrase 7 |
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| Ligand | BDBM50612156 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2286192 |
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| Ki | 0.390000±n/a nM |
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| Citation |  Ghatpande, NG; Jadhav, JS; Kaproormath, RV; Soliman, ME; Shaikh, MM A brief overview on recent advances in spiro[chromane-2,4'-piperidine]-4(3H)-one-functionalized compounds in medicinal chemistry research. Bioorg Med Chem28:0 (2020) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Carbonic anhydrase 7 |
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| Name: | Carbonic anhydrase 7 |
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| Synonyms: | CA-VII | CA7 | CAH7_HUMAN | Carbonate dehydratase VII | Carbonic anhydrase | Carbonic anhydrase VII | Carbonic anhydrase VII (CA VII) |
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| Type: | Enzyme |
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| Mol. Mass.: | 29664.11 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Human cloned isozyme. |
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| Residue: | 264 |
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| Sequence: | MTGHHGWGYGQDDGPSHWHKLYPIAQGDRQSPINIISSQAVYSPSLQPLELSYEACMSLS
ITNNGHSVQVDFNDSDDRTVVTGGPLEGPYRLKQFHFHWGKKHDVGSEHTVDGKSFPSEL
HLVHWNAKKYSTFGEAASAPDGLAVVGVFLETGDEHPSMNRLTDALYMVRFKGTKAQFSC
FNPKCLLPASRHYWTYPGSLTTPPLSESVTWIVLREPICISERQMGKFRSLLFTSEDDER
IHMVNNFRPPQPLKGRVVKASFRA
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| BDBM50612156 |
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| n/a |
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| Name | BDBM50612156 |
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| Synonyms: | CHEMBL5288389 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H21N3O7S |
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| Mol. Mass. | 447.462 |
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| SMILES | COc1ccc2C(=O)CC3(CCN(CC3)c3ccc(cc3[N+]([O-])=O)S(N)(=O)=O)Oc2c1 |
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| Structure | 
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