| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Dual specificity tyrosine-phosphorylation-regulated kinase 3 |
|---|
| Ligand | BDBM50097869 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_2290900 |
|---|
| IC50 | >10000±n/a nM |
|---|
| Citation |  Lindberg, MF; Deau, E; Arfwedson, J; George, N; George, P; Alfonso, P; Corrionero, A; Meijer, L Comparative Efficacy and Selectivity of Pharmacological Inhibitors of DYRK and CLK Protein Kinases. J Med Chem66:4106-4130 (2023) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Dual specificity tyrosine-phosphorylation-regulated kinase 3 |
|---|
| Name: | Dual specificity tyrosine-phosphorylation-regulated kinase 3 |
|---|
| Synonyms: | DYRK3 | DYRK3_HUMAN | Dual-specificity tyrosine-phosphorylation regulated kinase 3 |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 65747.26 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_1508026 |
|---|
| Residue: | 588 |
|---|
| Sequence: | MGGTARGPGRKDAGPPGAGLPPQQRRLGDGVYDTFMMIDETKCPPCSNVLCNPSEPPPPR
RLNMTTEQFTGDHTQHFLDGGEMKVEQLFQEFGNRKSNTIQSDGISDSEKCSPTVSQGKS
SDCLNTVKSNSSSKAPKVVPLTPEQALKQYKHHLTAYEKLEIINYPEIYFVGPNAKKRHG
VIGGPNNGGYDDADGAYIHVPRDHLAYRYEVLKIIGKGSFGQVARVYDHKLRQYVALKMV
RNEKRFHRQAAEEIRILEHLKKQDKTGSMNVIHMLESFTFRNHVCMAFELLSIDLYELIK
KNKFQGFSVQLVRKFAQSILQSLDALHKNKIIHCDLKPENILLKHHGRSSTKVIDFGSSC
FEYQKLYTYIQSRFYRAPEIILGSRYSTPIDIWSFGCILAELLTGQPLFPGEDEGDQLAC
MMELLGMPPPKLLEQSKRAKYFINSKGIPRYCSVTTQADGRVVLVGGRSRRGKKRGPPGS
KDWGTALKGCDDYLFIEFLKRCLHWDPSARLTPAQALRHPWISKSVPRPLTTIDKVSGKR
VVNPASAFQGLGSKLPPVVGIANKLKANLMSETNGSIPLCSVLPKLIS
|
|
|
|---|
| BDBM50097869 |
|---|
| n/a |
|---|
| Name | BDBM50097869 |
|---|
| Synonyms: | CHEMBL3589662 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C16H9IN2O2 |
|---|
| Mol. Mass. | 388.1593 |
|---|
| SMILES | OC(=O)c1nc2ccccc2c2[nH]c3c(I)cccc3c12 |
|---|
| Structure | 
|
|---|
Search and Browse
