| Reaction Details |
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 | Report a problem with these data |
| Target | Serine/threonine-protein kinase Nek5 |
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| Ligand | BDBM50355496 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2292041 |
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| Kd | 2300±n/a nM |
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| Citation |  Wells, CI; Kapadia, NR; Couņago, RM; Drewry, DH In depth analysis of kinase cross screening data to identify chemical starting points for inhibition of the Nek family of kinases. Medchemcomm9:44-66 (2018) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Serine/threonine-protein kinase Nek5 |
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| Name: | Serine/threonine-protein kinase Nek5 |
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| Synonyms: | NEK5 | NEK5_HUMAN |
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| Type: | PROTEIN |
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| Mol. Mass.: | 81473.82 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_655494 |
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| Residue: | 708 |
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| Sequence: | MDKYDVIKAIGQGAFGKAYLAKGKSDSKHCVIKEINFEKMPIQEKEASKKEVILLEKMKH
PNIVAFFNSFQENGRLFIVMEYCDGGDLMKRINRQRGVLFSEDQILGWFVQISLGLKHIH
DRKILHRDIKAQNIFLSKNGMVAKLGDFGIARVLNNSMELARTCIGTPYYLSPEICQNKP
YNNKTDIWSLGCVLYELCTLKHPFEGNNLQQLVLKICQAHFAPISPGFSRELHSLISQLF
QVSPRDRPSINSILKRPFLENLIPKYLTPEVIQEEFSHMLICRAGAPASRHAGKVVQKCK
IQKVRFQGKCPPRSRISVPIKRNAILHRNEWRPPAGAQKARSIKMIERPKIAAVCGHYDY
YYAQLDMLRRRAHKPSYHPIPQENTGVEDYGQETRHGPSPSQWPAEYLQRKFEAQQYKLK
VEKQLGLRPSSAEPNYNQRQELRSNGEEPRFQELPFRKNEMKEQEYWKQLEEIRQQYHND
MKEIRKKMGREPEENSKISHKTYLVKKSNLPVHQDASEGEAPVQMEFRSCCPGWSAMARS
WLTATSASQDIEKDLKQMRLQNTKESKNPEQKYKAKKGVKFEINLDKCISDENILQEEEA
MDIPNETLTFEDGMKFKEYECVKEHGDYTDKAFEKLHCPEAGFSTQTVAAVGNRRQWDGG
APQTLLQMMAVADITSTCPTGPDSESVLSVSRQEGKTKDPYSPVLILM
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| BDBM50355496 |
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| n/a |
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| Name | BDBM50355496 |
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| Synonyms: | CHEMBL1908397 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H20N4O |
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| Mol. Mass. | 332.399 |
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| SMILES | O=C(N1CCNCC1)c1ccc(\C=C\c2n[nH]c3ccccc23)cc1 |
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| Structure | 
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