| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Adenosine receptor A3 |
|---|
| Ligand | BDBM50199969 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_422431 (CHEMBL909306) |
|---|
| Ki | 312±n/a nM |
|---|
| Citation |  Cosyn, L; Palaniappan, KK; Kim, SK; Duong, HT; Gao, ZG; Jacobson, KA; Van Calenbergh, S 2-triazole-substituted adenosines: a new class of selective A3 adenosine receptor agonists, partial agonists, and antagonists. J Med Chem49:7373-83 (2006) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Adenosine receptor A3 |
|---|
| Name: | Adenosine receptor A3 |
|---|
| Synonyms: | AA3R_RAT | Adenosine A3 receptor | Adenosine receptor A2a and A3 | Adora3 |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 36643.73 |
|---|
| Organism: | Rattus norvegicus |
|---|
| Description: | ChEMBL_479910 |
|---|
| Residue: | 320 |
|---|
| Sequence: | MKANNTTTSALWLQITYITMEAAIGLCAVVGNMLVIWVVKLNRTLRTTTFYFIVSLALAD
IAVGVLVIPLAIAVSLEVQMHFYACLFMSCVLLVFTHASIMSLLAIAVDRYLRVKLTVRY
RTVTTQRRIWLFLGLCWLVSFLVGLTPMFGWNRKVTLELSQNSSTLSCHFRSVVGLDYMV
FFSFITWILIPLVVMCIIYLDIFYIIRNKLSQNLTGFRETRAFYGREFKTAKSLFLVLFL
FALCWLPLSIINFVSYFNVKIPEIAMCLGILLSHANSMMNPIVYACKIKKFKETYFVILR
ACRLCQTSDSLDSNLEQTTE
|
|
|
|---|
| BDBM50199969 |
|---|
| n/a |
|---|
| Name | BDBM50199969 |
|---|
| Synonyms: | 2-(4-cyclopentylmethyl-1,2,3-triazol-1-yl)-N6-methyl-9-(beta-Dribofuranosyl)adenine | CHEMBL219256 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C19H26N8O4 |
|---|
| Mol. Mass. | 430.4609 |
|---|
| SMILES | CNc1nc(nc2n(cnc12)[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O)-n1cc(CC2CCCC2)nn1 |r| |
|---|
| Structure | 
|
|---|
Search and Browse
