| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Caspase-7 |
|---|
| Ligand | BDBM50200313 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_408844 (CHEMBL909399) |
|---|
| IC50 | 29.2±n/a nM |
|---|
| Citation |  Kopka, K; Faust, A; Keul, P; Wagner, S; Breyholz, HJ; Höltke, C; Schober, O; Schäfers, M; Levkau, B 5-pyrrolidinylsulfonyl isatins as a potential tool for the molecular imaging of caspases in apoptosis. J Med Chem49:6704-15 (2006) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Caspase-7 |
|---|
| Name: | Caspase-7 |
|---|
| Synonyms: | Apoptotic protease Mch-3 | CASP-7 | CASP7 | CASP7_HUMAN | CMH-1 | Caspase | MCH3 | caspase 7, apoptosis-related cysteine peptidase |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 34273.91 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P55210 |
|---|
| Residue: | 303 |
|---|
| Sequence: | MADDQGCIEEQGVEDSANEDSVDAKPDRSSFVPSLFSKKKKNVTMRSIKTTRDRVPTYQY
NMNFEKLGKCIIINNKNFDKVTGMGVRNGTDKDAEALFKCFRSLGFDVIVYNDCSCAKMQ
DLLKKASEEDHTNAACFACILLSHGEENVIYGKDGVTPIKDLTAHFRGDRCKTLLEKPKL
FFIQACRGTELDDGIQADSGPINDTDANPRYKIPVEADFLFAYSTVPGYYSWRSPGRGSW
FVQALCSILEEHGKDLEIMQILTRVNDRVARHFESQSDDPHFHEKKQIPCVVSMLTKELY
FSQ
|
|
|
|---|
| BDBM50200313 |
|---|
| n/a |
|---|
| Name | BDBM50200313 |
|---|
| Synonyms: | (S)-5-[1-(2-methoxymethylpyrrolidinyl)sulfonyl]-1-(4-(tributylstannyl)benzyl)isatin | CHEMBL217822 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C33H48N2O5SSn |
|---|
| Mol. Mass. | 703.52 |
|---|
| SMILES | CCCC[Sn](CCCC)(CCCC)c1ccc(CN2C(=O)C(=O)c3cc(ccc23)S(=O)(=O)N2CCC[C@H]2COC)cc1 |
|---|
| Structure | 
|
|---|
Search and Browse
