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TargetAlpha-synuclein
LigandBDBM50614060
Substrate/Competitorn/a
Meas. Tech.ChEMBL_2295416
Kd 3.8±n/a nM
Citation Haque, RMaity, D Small molecule-based fluorescent probes for the detection of ?-Synuclein aggregation states. Bioorg Med Chem Lett86:0 (2023) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
Alpha-synuclein
Name:Alpha-synuclein
Synonyms:NACP | PARK1 | SNCA | SYUA_HUMAN
Type:Protein
Mol. Mass.:14451.42
Organism:Homo sapiens (Human)
Description:P37840
Residue:140
Sequence:
MDVFMKGLSKAKEGVVAAAEKTKQGVAEAAGKTKEGVLYVGSKTKEGVVHGVATVAEKTK
EQVTNVGGAVVTGVTAVAQKTVEGAGSIAAATGFVKKDQLGKNEEGAPQEGILEDMPVDP
DNEAYEMPSEEGYQDYEPEA
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  Blast E-value cutoff:
BDBM50614060
n/a
NameBDBM50614060
Synonyms:CHEMBL5270314
TypeSmall organic molecule
Emp. Form.C53H41N4O2
Mol. Mass.765.9177
SMILES[#8]-[#6]-[#6]-[#8]\[#6](\[#6]=[#6]\c1n(-c2ccccc2)c2cc3ccccc3cc2[n+]1-c1ccccc1)=[#6]/[#6]=[#6]-1\[#7](-c2cc3ccccc3cc2-[#7]-1-c1ccccc1)-c1ccccc1
Structure
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