| Reaction Details |
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 | Report a problem with these data |
| Target | Cholesterol side-chain cleavage enzyme, mitochondrial |
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| Ligand | BDBM50614278 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2296198 |
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| IC50 | 16±n/a nM |
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| Citation |  Gannett, C; Banks, P; Chuong, C; Weger-Lucarelli, J; Mevers, E; Lowell, AN Semisynthetic blasticidin S ester derivatives show enhanced antibiotic activity. RSC Med Chem14:782-789 (2023) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Cholesterol side-chain cleavage enzyme, mitochondrial |
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| Name: | Cholesterol side-chain cleavage enzyme, mitochondrial |
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| Synonyms: | CP11A_RAT | Cyp11a | Cyp11a-1 | Cyp11a1 | Cytochrome P450 11A1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 60603.33 |
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| Organism: | Rattus norvegicus |
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| Description: | ChEMBL_50353 |
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| Residue: | 526 |
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| Sequence: | MLAKGLCLRSVLVKSCQPFLSPVWQGPGLATGNGAGISSTNSPRSFNEIPSPGDNGWINL
YHFLRENGTHRIHYHHMQNFQKYGPIYREKLGNMESVYILDPKDAATLFSCEGPNPERYL
VPPWVAYHQYYQRPIGVLFKSSDAWRKDRIVLNQEVMAPDSIKNFVPLLEGVAQDFIKVL
HRRIKQQNSGKFSGDISDDLFRFAFESITSVVFGERLGMLEEIVDPESQRFIDAVYQMFH
TSVPMLNMPPDLFRLFRTKTWKDHAAAWDVIFSKADEYTQNFYWDLRQKRDFSKYPGVLY
SLLGGNKLPFKNIQANITEMLAGGVDTTSMTLQWNLYEMAHNLKVQEMLRAEVLAARRQA
QGDMAKMVQLVPLLKASIKETLRLHPISVTLQRYIVNDLVLRNYKIPAKTLVQVASYAMG
RESSFFPNPNKFDPTRWLEKSQNTTHFRYLGFGWGVRQCLGRRIAELEMTIFLINVLENF
RIEVQSIRDVGTKFNLILMPEKPIFFNFQPLKQDLGSTMPRKGDTV
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| BDBM50614278 |
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| n/a |
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| Name | BDBM50614278 |
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| Synonyms: | CHEMBL5285039 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H34N8O5 |
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| Mol. Mass. | 478.5453 |
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| SMILES | CCCCOC(=O)[C@H]1O[C@H](C=C[C@@H]1NC(=O)C[C@@H](N)CCN(C)C(N)=N)n1ccc(N)nc1=O |r,c:10| |
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| Structure | 
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