| Reaction Details |
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 | Report a problem with these data |
| Target | P2Y purinoceptor 14 |
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| Ligand | BDBM50343128 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2296988 |
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| Ki | 160±n/a nM |
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| Citation |  Conroy, S; Kindon, N; Kellam, B; Stocks, MJ Drug-like Antagonists of P2Y Receptors-From Lead Identification to Drug Development. J Med Chem59:9981-10005 (2016) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| P2Y purinoceptor 14 |
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| Name: | P2Y purinoceptor 14 |
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| Synonyms: | GPR105 | Insulin Receptor-Related Protein (INSRR) | KIAA0001 | P2RY14 | P2Y14_HUMAN | Purinergic receptor P2Y14 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 38991.62 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1502487 |
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| Residue: | 338 |
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| Sequence: | MINSTSTQPPDESCSQNLLITQQIIPVLYCMVFIAGILLNGVSGWIFFYVPSSKSFIIYL
KNIVIADFVMSLTFPFKILGDSGLGPWQLNVFVCRVSAVLFYVNMYVSIVFFGLISFDRY
YKIVKPLWTSFIQSVSYSKLLSVIVWMLMLLLAVPNIILTNQSVREVTQIKCIELKSELG
RKWHKASNYIFVAIFWIVFLLLIVFYTAITKKIFKSHLKSSRNSTSVKKKSSRNIFSIVF
VFFVCFVPYHIARIPYTKSQTEAHYSCQSKEILRYMKEFTLLLSAANVCLDPIIYFFLCQ
PFREILCKKLHIPLKAQNDLDISRIKRGNTTLESTDTL
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| BDBM50343128 |
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| n/a |
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| Name | BDBM50343128 |
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| Synonyms: | 2-(benzo[d][1,3]dioxol-5-yl)-N-(3-ethylphenyl)-4-o-tolyl-7,8-dihydropyrido[4,3-d]pyrimidine-6(5H)-carboxamide | CHEMBL1771456 |
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| Type | Small organic molecule |
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| Emp. Form. | C30H28N4O3 |
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| Mol. Mass. | 492.5683 |
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| SMILES | CCc1cccc(NC(=O)N2CCc3nc(nc(c3C2)-c2ccccc2C)-c2ccc3OCOc3c2)c1 |
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| Structure | 
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